1. GPCR/G Protein
  2. Vasopressin Receptor
  3. Felypressin acetate

Felypressin acetate (Synonyms: PLV-2 acetate)

Cat. No.: HY-A0182A
Handling Instructions

Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Felypressin acetate Chemical Structure

Felypressin acetate Chemical Structure

CAS No. : 914453-97-7

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Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin acetate is widely used in dental procedures[1][2].

IC50 & Target

Vasopressin 1[2]

In Vitro

Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures. The vasoconstrictor action of Felypressin seems to be mediated by V1 receptors of the blood vessel smooth muscle cells[1].

In Vivo

Felypressin can reduce toxicity during dental procedures. Felypressin increases the diastolic blood pressure of hypertensive patients with controlled blood pressure[1].
Cardiovascular effects of Felypressin (240 ng/kg; intravenous injection) are studied in Wistar rats. Felypressin induces a pressor effect. Felypressin depends on V1 receptors to induce pressor and bradycardic effects, and that it produces a high relationship between bradycardia and mean arterial pressure variation depending on area postrema and central V1 receptors[2].






CFFQNCPKG-NH2 (Disulfide bridge: Cys1-Cys6)

Sequence Shortening

{Cys}{Phe}{Phe}{Gln}{Asn}{Cys}{Pro}{Lys}{Gly}-NH2 (Disulfide bridge: Cys1-Cys6)


Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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This equation is commonly abbreviated as: C1V1 = C2V2

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FelypressinPLV-2PLV2PLV 2Vasopressin ReceptorVasopressin 1vasoconstrictorhormonepituitaryanestheticdentalnon-catecholamineArginineInhibitorinhibitorinhibit

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