Antifungal agent 47
Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide.
For research use only. We do not sell to patients.
- CAS No.: 2719867-46-4
- Formula: C39H38BrClNO2P
- Molecular Weight:699.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Antifungal agent 47 (compound 3b) shows antifungal activity against five phytopathogenic fungi (P. capsici, R. solani, B. cinerea, P. aphanidermatum and S. sclerotiorum), with EC50 values of 12.70, 21.74, 22.42, 11.00, and 4.78 μM, respectively[1].
Antifungal agent 47 (35 μM, 3 h) inhibits ATP production of P. capsici mycelium, with inhibition rate of 61.70 ± 3.64%[1].
Antifungal agent 47 exhibits greatly improved action on mitochondria, such as by destroying the mitochondrial function of pathogens, causing mitochondrial swelling, weakening its influence on cell wall morphology, and so on[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Tomato fruits in both protective and curative modes[1]
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Dosage:200 μg/mL
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Administration:
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Result:Inhibited the growth of B. cinerea in tomato fruits. It received 59.01% control efficacy in protective mode and 53.56% control efficacy in curative mode.
Chemical Information
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CAS No. 2719867-46-4
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Molecular Weight 699.06
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Formula C39H38BrClNO2P
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SMILES
O=C(OCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)/C=C(C4=CC=C(C(C)(C)C)C=C4)\C5=CC(Cl)=NC=C5.[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)