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  3. Antifungal agent 47

Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide.

For research use only. We do not sell to patients.

Antifungal agent 47 Chemical Structure

Antifungal agent 47 Chemical Structure

CAS No. : 2719867-46-4

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Description

Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide[1].

In Vitro

Antifungal agent 47 (compound 3b) shows antifungal activity against five phytopathogenic fungi (P. capsici, R. solani, B. cinerea, P. aphanidermatum and S. sclerotiorum), with EC50 values of 12.70, 21.74, 22.42, 11.00, and 4.78 μM, respectively[1].
Antifungal agent 47 (35 μM, 3 h) inhibits ATP production of P. capsici mycelium, with inhibition rate of 61.70 ± 3.64%[1].
Antifungal agent 47 exhibits greatly improved action on mitochondria, such as by destroying the mitochondrial function of pathogens, causing mitochondrial swelling, weakening its influence on cell wall morphology, and so on[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Antifungal agent 47 (compound 3b) (200 μg/mL) shows fungicidal activity against B. cinerea in tomato fruits[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Tomato fruits in both protective and curative modes[1]
Dosage: 200 μg/mL
Administration:
Result: Inhibited the growth of B. cinerea in tomato fruits. It received 59.01% control efficacy in protective mode and 53.56% control efficacy in curative mode.
Molecular Weight

699.06

Formula

C39H38BrClNO2P

CAS No.
SMILES

O=C(OCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)/C=C(C4=CC=C(C(C)(C)C)C=C4)\C5=CC(Cl)=NC=C5.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Antifungal agent 47 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Antifungal agent 47
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HY-149067
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