Antifungal agent 47
Antifungal agent 47 (compound 3b) shows the highest and broad-spectrum fungicidal activity, strong respiratory inhibition activity, and adenosine 5′-triphosphate synthesis inhibition activity. Antifungal agent 47 is potential as a fungicide.
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- CAS No.: 2719867-46-4
- Formule: C39H38BrClNO2P
- Masse moléculaire:699.06
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Antifungal agent 47 (compound 3b) shows antifungal activity against five phytopathogenic fungi (P. capsici, R. solani, B. cinerea, P. aphanidermatum and S. sclerotiorum), with EC50 values of 12.70, 21.74, 22.42, 11.00, and 4.78 μM, respectively[1].
Antifungal agent 47 (35 μM, 3 h) inhibits ATP production of P. capsici mycelium, with inhibition rate of 61.70 ± 3.64%[1].
Antifungal agent 47 exhibits greatly improved action on mitochondria, such as by destroying the mitochondrial function of pathogens, causing mitochondrial swelling, weakening its influence on cell wall morphology, and so on[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Tomato fruits in both protective and curative modes[1]
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Dosage:200 μg/mL
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Administration:
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Result:Inhibited the growth of B. cinerea in tomato fruits. It received 59.01% control efficacy in protective mode and 53.56% control efficacy in curative mode.
Chemical Information
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CAS No. 2719867-46-4
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Masse moléculaire 699.06
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Formule C39H38BrClNO2P
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SMILES
O=C(OCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)/C=C(C4=CC=C(C(C)(C)C)C=C4)\C5=CC(Cl)=NC=C5.[Br-]
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)