Maleimide-DTPA
Maleimide-DTPA (MDTPA) is a monoreactive DTPA derivative (MDTPA) with maleimide group as peptide binding site, which can be combined with radionuclides to prepare radionuclide conjugates (RDC). Maleimide-DTPA can chelate indium-111 (111In) and label peptides and peptides with indium-111. For example, it has high stability when combined with OST7 incubated in human serum, which is better than cyclic cDTPA. Maleimide-DTPA is a good material for medical imaging or treatment.
For research use only. We do not sell to patients.
- CAS No.: 180152-82-3
- Formula: C20H29N5O11
- Molecular Weight:515.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Radionuclide-Drug Conjugates (RDCs) Isoforms
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Biological Activity
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RDC Bifunctional Chelator |
Chemical Information
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CAS No. 180152-82-3
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Molecular Weight 515.47
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Formula C20H29N5O11
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SMILES
O=C(NCCN1C(C=CC1=O)=O)CN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC(O)=O
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Synonyms
MDTPA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : ≥ 103 mg/mL (199.82 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9400 mL | 9.6999 mL | 19.3998 mL | 48.4994 mL |
| 5 mM | 0.3880 mL | 1.9400 mL | 3.8800 mL | 9.6999 mL | |
| 10 mM | 0.1940 mL | 0.9700 mL | 1.9400 mL | 4.8499 mL | |
| 15 mM | 0.1293 mL | 0.6467 mL | 1.2933 mL | 3.2333 mL | |
| 20 mM | 0.0970 mL | 0.4850 mL | 0.9700 mL | 2.4250 mL | |
| 25 mM | 0.0776 mL | 0.3880 mL | 0.7760 mL | 1.9400 mL | |
| 30 mM | 0.0647 mL | 0.3233 mL | 0.6467 mL | 1.6166 mL | |
| 40 mM | 0.0485 mL | 0.2425 mL | 0.4850 mL | 1.2125 mL | |
| 50 mM | 0.0388 mL | 0.1940 mL | 0.3880 mL | 0.9700 mL | |
| 60 mM | 0.0323 mL | 0.1617 mL | 0.3233 mL | 0.8083 mL | |
| 80 mM | 0.0242 mL | 0.1212 mL | 0.2425 mL | 0.6062 mL | |
| 100 mM | 0.0194 mL | 0.0970 mL | 0.1940 mL | 0.4850 mL |