1. GPCR/G Protein
  2. Adenosine Receptor
  3. ISAM-140

ISAM-140 

Cat. No.: HY-111082
Handling Instructions

ISAM-140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM.

For research use only. We do not sell to patients.

ISAM-140 Chemical Structure

ISAM-140 Chemical Structure

CAS No. : 932191-62-3

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Description

ISAM-140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM[1].

IC50 & Target

hA2B

3.49 nM (Ki)

In Vitro

ISAM-140 (22b) (0.1-100 µM) inhibits NECA (5'-N-ethylcarboxamido adenosine)-stimulated cAMP accumulation[1].
ISAM-140 shows a KB value of 27.00 nM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

337.37

Formula

C19H19N3O3

CAS No.
SMILES

O=C(C1=C(C)N=C2NC3=CC=CC=C3N2C1C4=CC=CO4)OC(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
ISAM-140
Cat. No.:
HY-111082
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