1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Fosfructose trisodium

Fosfructose trisodium  (Synonyms: Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium)

Cat. No.: HY-106950A Purity: ≥99.0%
COA Handling Instructions

Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

For research use only. We do not sell to patients.

Fosfructose trisodium Chemical Structure

Fosfructose trisodium Chemical Structure

CAS No. : 38099-82-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 66 In-stock
Solution
10 mM * 1 mL in Water USD 66 In-stock
Solid
100 mg USD 60 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Fosfructose trisodium:

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Description

Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

Molecular Weight

406.06

Formula

C6H11Na3O12P2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H](C(COP(O)(O[Na])=O)=O)[C@@H]([C@@H](COP(O[Na])(O[Na])=O)O)O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 150 mg/mL (369.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4627 mL 12.3135 mL 24.6269 mL
5 mM 0.4925 mL 2.4627 mL 4.9254 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (246.27 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.4627 mL 12.3135 mL 24.6269 mL 61.5673 mL
5 mM 0.4925 mL 2.4627 mL 4.9254 mL 12.3135 mL
10 mM 0.2463 mL 1.2313 mL 2.4627 mL 6.1567 mL
15 mM 0.1642 mL 0.8209 mL 1.6418 mL 4.1045 mL
20 mM 0.1231 mL 0.6157 mL 1.2313 mL 3.0784 mL
25 mM 0.0985 mL 0.4925 mL 0.9851 mL 2.4627 mL
30 mM 0.0821 mL 0.4104 mL 0.8209 mL 2.0522 mL
40 mM 0.0616 mL 0.3078 mL 0.6157 mL 1.5392 mL
50 mM 0.0493 mL 0.2463 mL 0.4925 mL 1.2313 mL
60 mM 0.0410 mL 0.2052 mL 0.4104 mL 1.0261 mL
80 mM 0.0308 mL 0.1539 mL 0.3078 mL 0.7696 mL
100 mM 0.0246 mL 0.1231 mL 0.2463 mL 0.6157 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Fosfructose trisodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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