1. GPCR/G Protein
  2. P2Y Receptor
  3. N6-(4-Hydroxybenzyl)adenosine

N6-(4-Hydroxybenzyl)adenosine (Synonyms: Para-topolin riboside)

Cat. No.: HY-18775 Purity: 99.66%
Handling Instructions

N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM).

For research use only. We do not sell to patients.

N6-(4-Hydroxybenzyl)adenosine Chemical Structure

N6-(4-Hydroxybenzyl)adenosine Chemical Structure

CAS No. : 110505-75-4

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 92 In-stock
Estimated Time of Arrival: December 31
10 mg USD 84 In-stock
Estimated Time of Arrival: December 31
50 mg USD 288 In-stock
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100 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

N6-(4-Hydroxybenzyl)adenosine is a inhibitor of platelet aggregation induced in vitro by collagen and their activity range was demonstrated (IC50: 6.77-141 μM). IC50 value: 6.77-141 μM Target: P2Y12receptor Anti-aggregation activity of N6-(4-Hydroxybenzyl)adenosine could involve an interaction with the P2Y12receptor binding site.

Molecular Weight

373.36

Formula

C₁₇H₁₉N₅O₅

CAS No.

110505-75-4

SMILES

OC[[email protected]@H]1[[email protected]]([[email protected]]([[email protected]](N2C=NC3=C2N=CN=C3NCC4=CC=C(O)C=C4)O1)O)O

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Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (267.84 mM)

H2O : < 0.1 mg/mL (insoluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6784 mL 13.3919 mL 26.7838 mL
5 mM 0.5357 mL 2.6784 mL 5.3568 mL
10 mM 0.2678 mL 1.3392 mL 2.6784 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.70 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.70 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.70 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.66%

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Keywords:

N6-(4-Hydroxybenzyl)adenosinePara-topolin ribosideP2Y ReceptorInhibitorinhibitorinhibit

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Product name:
N6-(4-Hydroxybenzyl)adenosine
Cat. No.:
HY-18775
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