2’-Chloro-N6-(3-methoxy)benzyl adenosine
Based on 1 Customer Validation
2’-Chloro-N6-(3-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.83%
- CAS No.: 722504-73-6
- Formula: C18H20ClN5O5
- Molecular Weight:421.83
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 722504-73-6
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Appearance Solid
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Molecular Weight 421.83
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Formula C18H20ClN5O5
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Color White to off-white
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SMILES
ClC1=NC2=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C(NCC4=CC=CC(OC)=C4)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (237.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [Content Brief]
[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3706 mL | 11.8531 mL | 23.7062 mL | 59.2656 mL |
| 5 mM | 0.4741 mL | 2.3706 mL | 4.7412 mL | 11.8531 mL | |
| 10 mM | 0.2371 mL | 1.1853 mL | 2.3706 mL | 5.9266 mL | |
| 15 mM | 0.1580 mL | 0.7902 mL | 1.5804 mL | 3.9510 mL | |
| 20 mM | 0.1185 mL | 0.5927 mL | 1.1853 mL | 2.9633 mL | |
| 25 mM | 0.0948 mL | 0.4741 mL | 0.9482 mL | 2.3706 mL | |
| 30 mM | 0.0790 mL | 0.3951 mL | 0.7902 mL | 1.9755 mL | |
| 40 mM | 0.0593 mL | 0.2963 mL | 0.5927 mL | 1.4816 mL | |
| 50 mM | 0.0474 mL | 0.2371 mL | 0.4741 mL | 1.1853 mL | |
| 60 mM | 0.0395 mL | 0.1976 mL | 0.3951 mL | 0.9878 mL | |
| 80 mM | 0.0296 mL | 0.1482 mL | 0.2963 mL | 0.7408 mL | |
| 100 mM | 0.0237 mL | 0.1185 mL | 0.2371 mL | 0.5927 mL |
2’-Chloro-N6-(3-methoxy)benzyl adenosine Related Classifications
HY-152330 Related Classifications
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