1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 2’-Chloro-N6-(3-methoxy)benzyl adenosine

2’-Chloro-N6-(3-methoxy)benzyl adenosine 

Cat. No.: HY-152330 Purity: 99.83%
Handling Instructions Technical Support

2’-Chloro-N6-(3-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

2’-Chloro-N6-(3-methoxy)benzyl adenosine

2’-Chloro-N6-(3-methoxy)benzyl adenosine Chemical Structure

CAS No. : 722504-73-6

Size Price Stock Quantity
1 mg In-stock
5 mg In-stock
10 mg In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 Customer Validation

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

2’-Chloro-N6-(3-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Molecular Weight

421.83

Formula

C18H20ClN5O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC1=NC2=C(N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C(NCC4=CC=CC(OC)=C4)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (237.06 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3706 mL 11.8531 mL 23.7062 mL
5 mM 0.4741 mL 2.3706 mL 4.7412 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3706 mL 11.8531 mL 23.7062 mL 59.2656 mL
5 mM 0.4741 mL 2.3706 mL 4.7412 mL 11.8531 mL
10 mM 0.2371 mL 1.1853 mL 2.3706 mL 5.9266 mL
15 mM 0.1580 mL 0.7902 mL 1.5804 mL 3.9510 mL
20 mM 0.1185 mL 0.5927 mL 1.1853 mL 2.9633 mL
25 mM 0.0948 mL 0.4741 mL 0.9482 mL 2.3706 mL
30 mM 0.0790 mL 0.3951 mL 0.7902 mL 1.9755 mL
40 mM 0.0593 mL 0.2963 mL 0.5927 mL 1.4816 mL
50 mM 0.0474 mL 0.2371 mL 0.4741 mL 1.1853 mL
60 mM 0.0395 mL 0.1976 mL 0.3951 mL 0.9878 mL
80 mM 0.0296 mL 0.1482 mL 0.2963 mL 0.7408 mL
100 mM 0.0237 mL 0.1185 mL 0.2371 mL 0.5927 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
2’-Chloro-N6-(3-methoxy)benzyl adenosine
Cat. No.:
HY-152330
Quantity:
MCE Japan Authorized Agent: