KRL74
KRL74 is a cyclic peptide inhibitor for interaction between the p6 domain of the HIV Gag protein and the UEV domain of the human TSG101 protein(p6/UEV) with an IC50 of 5.44 μM and a Kd of 11.9 μM. KRL74 inhibits the budding process of HIV from host cells with an IC50 of 2 μM in virus-like particle (VLP) budding assay.
For research use only. We do not sell to patients.
- CAS No.: 2423969-43-9
- Formula: C50H61ClN10O9
- Molecular Weight:981.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2423969-43-9
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Molecular Weight 981.53
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Formula C50H61ClN10O9
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Sequence
cyclo(Ser-Gly-Trp-Ile-{Phe<4-Cl>}-Trp-Ala-Val)
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Sequence Shortening
cyclo(SGWI-{Phe<4-Cl>}-WAV)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KRL74 Related Classifications
HY-P10845 Related Classifications
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