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ATP ditromethamine

(Synonyms: Adenosine 5'-triphosphate ditromethamine)
164 Cited Publications
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Based on 164 publication(s) in Google Scholar

ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine) is a central component of energy storage and metabolism in vivo. ATP ditromethamine provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP ditromethamine is an important endogenous signaling molecule in immunity and inflammation.

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  • CAS No.: 102047-34-7
  • Formula: C18H38N7O19P3
  • Molecular Weight:749.45
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • ATP ditromethamine Chemical Structure
    ATP ditromethamine Chemical Structure
  • Experimental Validation Results for ATP ditromethamine
  • Experimental Validation Results for ATP ditromethamine
  • Experimental Validation Results for ATP ditromethamine
  • Experimental Validation Results for ATP ditromethamine
  • Experimental Validation Results for ATP ditromethamine
  • Experimental Validation Results for ATP ditromethamine
CAS No.: 102047-34-7
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WBCell Proliferation/Viability AssayRT-PCR
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  • ATP ditromethamine Chemical Structure
    ATP ditromethamine Chemical Structure
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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Immunity. 2024 Mar 12;57(3):495-512.e11. [Abstract]

    Customer Validation
     Representative western blots and analyses of the following proteins in BV2 cells treated with vehicle (Con), LPS (200 ng/ml, 3 h), LPS + ATP (3 mM, 30 min), or LPS + ATP-siNKAα1.

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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Transl Res. 2023 May:255:1-13. [Abstract]

    Customer Validation
     LPS/ATP treatment significantly promotes expression of NLRP3 and production of N-GSDMD in HAEC. HAEC are pretreated with LPS (500ng/ml) for 5 h and then stimulated with ATP (5 mM) for 1 h.

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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Cell Death Differ. 2022 Feb;29(2):439-450. [Abstract]

    Customer Validation
     Primary BMDM cells were isolated from WT and Trim21-/- C57BL/6 mice. Cells were primed with 1 μg/mL LPS for 2 h followed by 5 mM ATP or 20 μM Nig or 30 μM flagellin for 30 min. Cell viability are determined by the Cell Counting Kit-8.

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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Crit Care. 2021 Oct 12;25(1):356. [Abstract]

    Customer Validation
     Stimulation of Raw264.7 macrophages with PBS/PBS-Exo/TNF-Exo for 24 h and treatment with PBS, 5 mM ATP or 20 mM nigericin for 2 h. Cleavage of GSDMD by western blot. GSDMD-FL: full-length GSDMD, GSDMD-N: N-terminal cleavage products of GSDMD.

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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2020 Feb 18;11(2):132.  [Abstract]

    Customer Validation
     KCs were stimulated with 100 ng/mL LPS for 4 hours and subsequently treated them with 5 mM ATP for 2 hours to induce pyroptosis. The RNA level of lnc-Lfar1 was determined by qRT-PCR.

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    ATP ditromethamine purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2020 Feb 18;11(2):132.  [Abstract]

    Customer Validation
     KCs were transfected with lnc-Lfar1 siRNA for 24 h, followed by stimulation with 100 ng/ml LPS for 4 h and subsequently treated with 5 mM ATP or 100 ng/ml for 2 h to induce pyroptosis. a, b The protein level of NLRP3, Caspase1 and GSDMD was determined by western blot. GAPDH was used as an internal control.

  • ATP ditromethamine