1. Membrane Transporter/Ion Channel Neuronal Signaling Anti-infection
  2. nAChR SARS-CoV
  3. Conofurin-Delta

Conofurin-Delta is a potent α7 nAChR inhibitor with an IC50 of 177 nM. Conofurin-Delta also inhibits α9α10 nAChR with an IC50 of 98.1 nM. Conofurin-Delta may be used in SARS-CoV-2 infection research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Conofurin-Delta

Conofurin-Delta Chemical Structure

CAS No. : 3093661-13-0

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Description

Conofurin-Delta is a potent α7 nAChR inhibitor with an IC50 of 177 nM. Conofurin-Delta also inhibits α9α10 nAChR with an IC50 of 98.1 nM. Conofurin-Delta may be used in SARS-CoV-2 infection research[1].

IC50 & Target

IC50: 177 nM (α7 nAChR); 98.1 nM (α9α10 nAChR)[1]

Molecular Weight

1745.01

Formula

C64H109N31O19S4

CAS No.
Sequence

Gly-Cys-Cys-Ser-His-Pro-Ala-Cys-Ser-Arg-Arg-Arg-Ala-Arg-Ser-Cys-NH2 (Disulfide bridge: Cys2-Cys8,Cys3-Cys16)

Sequence Shortening

GCCSHPACSRRRARSC-NH2 (Disulfide bridge: Cys2-Cys8,Cys3-Cys16)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Conofurin-Delta
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HY-P11470
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