Cyclo(Gly-L-Pro)
Based on 1 Customer Validation
Cyclo(Gly-L-Pro) is a Alkaloids product that can be isolated from the roots of Panax notoginseng (Burk.)F.H.Chen.
For research use only. We do not sell to patients.
- Purity: 99.86%
- CAS No.: 3705-27-9
- Formula: C7H10N2O2
- Molecular Weight:154.17
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Storage:
Stored under nitrogen, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
4.5 μg/mL
Compound: 1
|
Inhibition of LPS-induced TNF-alpha production in mouse RAW264.7 cells pretreated with compound for 1 hr followed by addition of 1 ug/ml LPS for 6 hrs by ELISA
Inhibition of LPS-induced TNF-alpha production in mouse RAW264.7 cells pretreated with compound for 1 hr followed by addition of 1 ug/ml LPS for 6 hrs by ELISA
|
[PMID: 26546220] |
Chemical Information
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CAS No. 3705-27-9
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Appearance Solid
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Molecular Weight 154.17
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Formula C7H10N2O2
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Color White to off-white
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SMILES
O=C1[C@@]2([H])N(CCC2)C(CN1)=O
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Sequence
Cyclo(Pro-Gly)
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Sequence Shortening
Cyclo(PG)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Stored under nitrogen, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
H2O : ≥ 200 mg/mL (1297.27 mM)
DMSO : 25 mg/mL (162.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (246 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 6.4863 mL | 32.4317 mL | 64.8635 mL | 162.1587 mL |
| 5 mM | 1.2973 mL | 6.4863 mL | 12.9727 mL | 32.4317 mL | |
| 10 mM | 0.6486 mL | 3.2432 mL | 6.4863 mL | 16.2159 mL | |
| 15 mM | 0.4324 mL | 2.1621 mL | 4.3242 mL | 10.8106 mL | |
| 20 mM | 0.3243 mL | 1.6216 mL | 3.2432 mL | 8.1079 mL | |
| 25 mM | 0.2595 mL | 1.2973 mL | 2.5945 mL | 6.4863 mL | |
| 30 mM | 0.2162 mL | 1.0811 mL | 2.1621 mL | 5.4053 mL | |
| 40 mM | 0.1622 mL | 0.8108 mL | 1.6216 mL | 4.0540 mL | |
| 50 mM | 0.1297 mL | 0.6486 mL | 1.2973 mL | 3.2432 mL | |
| 60 mM | 0.1081 mL | 0.5405 mL | 1.0811 mL | 2.7026 mL | |
| 80 mM | 0.0811 mL | 0.4054 mL | 0.8108 mL | 2.0270 mL | |
| 100 mM | 0.0649 mL | 0.3243 mL | 0.6486 mL | 1.6216 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.