Polymyxin B nonapeptide TFA (Standard)
Polymyxin B nonapeptide (TFA) (Standard) is the analytical standard of Polymyxin B nonapeptide (TFA). This product is intended for research and analytical applications. Polymyxin B nonapeptide TFA is a cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue. Polymyxin B nonapeptide TFA is less toxic, lacks bactericidal activity, and retains its ability to render gram-negative bacteria susceptible to several antibiotics by permeabilizing their outer membranes[1][2][3].
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 2220175-42-6
- Formula: C43H74N14O11.5C2HF3O2
- Molecular Weight:1533.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2220175-42-6
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Molecular Weight 1533.25
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Formula C43H74N14O11.5C2HF3O2
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SMILES
FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.O=C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@]1([H])[C@H](O)C)=O)CCN)=O)CCN)=O)CC(C)C)[C@H](NC([C@@H](NC([C@H](CCNC1=O)NC([C@H](CCN)NC([C@@H](N)[C@H](O)C)=O)=O)=O)CCN)=O)CC2=CC=CC=C2.FC(F)(F)C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Al-Marzooq F, et al. Discerning the role of polymyxin B nonapeptide in restoring the antibacterial activity of azithromycin against antibiotic-resistant Escherichia coli. Front Microbiol. 2022 Sep 21;13:998671. [Content Brief]
[2]. Danner RL,et al. Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide. Antimicrob Agents Chemother. 1989 Sep;33(9):1428-34. [Content Brief]
[3]. Ofek I, et al. Antibacterial synergism of polymyxin B nonapeptide and hydrophobic antibiotics in experimental gram-negative infections in mice. Antimicrob Agents Chemother. 1994 Feb;38(2):374-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polymyxin B nonapeptide TFA (Standard) Related Classifications
HY-106783AR Related Classifications
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