2. Anti-infection Neuronal Signaling GPCR/G Protein
  3. Parasite Dopamine Receptor
  4. Flubenzimine

Flubenzimine is a cyclic amidine acaricide. Flubenzimine significantly reduces the levels of dopamine and its precursor dopa in Rhizoglyphus echinopus.

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Flubenzimine

Flubenzimine Chemical Structure

CAS No. : 37893-02-0

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Flubenzimine Related Antibodies

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Description

Flubenzimine is a cyclic amidine acaricide. Flubenzimine significantly reduces the levels of dopamine and its precursor dopa in Rhizoglyphus echinopus[1].

In Vitro

Flubenzimine (100 μM; 30 min) inhibits the degradation of 2-phenylethylamine (PEA) by 16% in whole tissue homogenates of the bulb mite Rhizoglyphus echinopus[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Flubenzimine Related Antibodies
In Vivo

Flubenzimine (1.0 mg/mL; pre-coated on the surface of exposure chambers; 1-24 h) causes a statistically significant, time-dependent decrease in dopamine levels in adult female Pyemotes ventricosus[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult female bulb mites (2-6 days old, 10 mg total mass per group)[1]
Dosage: 1.0 mg/mL
Administration: precoated onto exposure chamber surfaces; 1 hour or 24 hours exposure; held in darkness at 25°C
Result: Reduced DA levels to 55% of control levels after 1 hour exposure.
Reduced DOPA levels to 94% of control levels after 1 hour exposure.
Reduced DA levels to 33% of control levels after 24 hours exposure.
Reduced DOPA levels to 48% of control levels after 24 hours exposure.
Molecular Weight

416.35

Formula

C17H10F6N4S
CAS No.
SMILES

FC(F)(F)N=C1SC(=NC=2C=CC=CC2)N(C=3C=CC=CC3)C1=NC(F)(F)F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Flubenzimine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Flubenzimine37893-02-0ParasiteDopamine Receptordopaminebulb mitesadult female bulb mites2-phenylethylaminecyclic amidinereducing agentRhizoglyphus echinopusInhibitorinhibitorinhibit

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