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3′,5′-DiOA-dC

3’,5’-DiOA-dC is a hydrophobic nucleotide lipid and a ligand for the STING agonist c-di-GMP (CDG). 3’,5’-DiOA-dC can assemble with CDG and form stable cyclic dinucleotide nanoparticles via various supramolecular forces driven by molecular recognition. 3’,5’-DiOA-dC can decrease tumor weight and volume, increase CD8 T cell, neutrophils as well as NK cell counts in tumor microenvironment in combination with CDG. 3’,5’-DiOA-dC also increases the levels of TNF-α and IFN-γ in murine melanoma model.

For research use only. We do not sell to patients.

  • Formula: C45H77N3O6
  • Molecular Weight:756.11
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • 3′,5′-DiOA-dC Chemical Structure
    3′,5′-DiOA-dC Chemical Structure
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  • 3′,5′-DiOA-dC Chemical Structure
    3′,5′-DiOA-dC Chemical Structure
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  • 3′,5′-DiOA-dC