Ulicyclamide
Ulicyclamide is a cytotoxic cyclic peptide found in the tunicate Lissoclinum patella.Ulicyclamide inhibits DNA and RNA synthesis in leukemia cells. Ulicyclamide can be used for the research of leukemia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 74839-81-9
- Formel: C33H39N7O5S2
- Molecular Weight:677.84
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Ulicyclamide (dose-response curve range; 48 h) is cytotoxic against cultured L1210 mouse leukemia cells in vitro, with an IC50 of 13 μg/mL after 48 h of incubation[1].
Ulicyclamide (dose-response curve range; 2 h) potently inhibits both DNA and RNA syntheses (IC50 = 2.2 μg/mL for each) in cultured L1210 mouse leukemia cells after 2 hr of incubation, while having no effect on protein synthesis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 74839-81-9
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Molecular Weight 677.84
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Formel C33H39N7O5S2
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SMILES
O=C(N1CCC[C@]1(C2=N[C@]([H])3[C@H](O2)C)[H])[C@@H](NC(C4=CSC([C@H](NC(C5=CSC([C@@H](NC3=O)[C@@H](C)CC)=N5)=O)C)=N4)=O)CC6=CC=CC=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)