m-PEG750-OH
Based on 1 Customer Validation
m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 9004-74-4
- Molecular Weight:750 (Average)
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
m-PEG-OH can be used to encapsulate anticancer drugs. Hydrophobic anticancer agent Paclitaxel (HY-B0015) encapsulated in micelles exhibits stronger cancer cell-killing activity than free Paclitaxel. In addition, it preferentially accumulates in tumor tissues and shows only limited distribution in healthy organs[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-74-4
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Appearance Oil
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Molecular Weight 750 (Average)
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Color White to off-white
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SMILES
COCCOCCO.[n]
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Synonyms
mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 16.67 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Riccio G, et al. Monogalactosyldiacylglycerol and Sulfolipid Synthesis in Microalgae. Mar Drugs. 2020;18(5):237. Published 2020 May 1. [Content Brief]
[2]. Lee AL, et al. The use of cholesterol-containing biodegradable block copolymers to exploit hydrophobic interactions for the delivery of anticancer drugs. Biomaterials. 2012;33(6):1921-1928. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)