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  3. m-PEG750-OH

m-PEG750-OH  (Synonyms: mPEG750-Hydroxy; Polyethylene glycol monomethyl ether 750)

Cat. No.: HY-140696H Purity: 98.0%
Handling Instructions Technical Support

m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery.

For research use only. We do not sell to patients.

m-PEG750-OH

m-PEG750-OH Chemical Structure

CAS No. : 9004-74-4

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Based on 1 publication(s) in Google Scholar

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Description

m-PEG750-OH (mPEG750-Hydroxy) is a monomethoxypolyethylene glycol and also a macroinitiator for organocatalytic ring-opening polymerization of aliphatic cyclic carbonate monomers. m-PEG750-OH can participate in the synthesis of amphiphilic block copolymers. Amphiphilic block copolymers can be used to prepare nanoscale micelles for active drug delivery[1][2].

In Vitro

m-PEG-OH can be used to encapsulate anticancer drugs. Hydrophobic anticancer agent Paclitaxel (HY-B0015) encapsulated in micelles exhibits stronger cancer cell-killing activity than free Paclitaxel. In addition, it preferentially accumulates in tumor tissues and shows only limited distribution in healthy organs[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

750 (Average)

CAS No.
Appearance

Oil

Color

White to off-white

SMILES

COCCOCCO.[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 16.67 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
m-PEG750-OH
Cat. No.:
HY-140696H
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