2. Stem Cell/Wnt
  3. Porcupine Wnt
  4. WNT3Ap

WNT3Ap is a polypeptide corresponding to the hairpin 2 domain of the WNT3A protein. WNT3Ap undergoes palmitoylation modification catalyzed by PORCN. WNT3Ap is a key compound for elucidating the molecular mechanism of the Wnt signaling pathway and for developing PORCN inhibitors.

For research use only. We do not sell to patients.

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WNT3Ap

WNT3Ap Chemical Structure

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WNT3Ap Related Antibodies

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Description

WNT3Ap is a polypeptide corresponding to the hairpin 2 domain of the WNT3A protein. WNT3Ap undergoes palmitoylation modification catalyzed by PORCN. WNT3Ap is a key compound for elucidating the molecular mechanism of the Wnt signaling pathway and for developing PORCN inhibitors[1].

In Vitro

WNT3Ap (50 μM; 37°C for 30 minutes) undergoes acylation by PORCN in vitro, with a Km value of 14.29 μM for palmitoyl-CoA[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

WNT3Ap Related Antibodies
Molecular Weight

2518.98

Formula

C108H164N32O28S5
Sequence

Met-His-Leu-Lys-Cys-Lys-Cys-His-Gly-Leu-Ser-Gly-Ser-Cys-Glu-Val-Lys-Thr-Cys-Trp-Trp-Ser-NH2 (Disulfide bridge:Cys5-Cys19,Cys7-Cys14)
Sequence Shortening

MHLKCKCHGLSGSCEVKTCWWS-NH2 (Disulfide bridge:Cys5-Cys19,Cys7-Cys14)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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WNT3Ap Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WNT3ApPorcupineWntwnttumorsInhibitorinhibitorinhibit

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