N6-Aminoadenosine
N6-Aminoadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
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- CAS. Nr.: 5746-27-0
- Formel: C10H14N6O4
- Molecular Weight:282.26
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Caco-2 | GI50 |
1.03 μM
Compound: 5
|
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
Antiproliferative activity against human Caco2 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| HeLa | GI50 |
0.52 μM
Compound: 5
|
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| HT-29 | GI50 |
1.44 μM
Compound: 5
|
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| K562 | GI50 |
0.61 μM
Compound: 5
|
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
Antiproliferative activity against human K562 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
| KB | CC50 |
2.26 μM
Compound: 2a
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 17548196] |
| MCF7 | GI50 |
0.35 μM
Compound: 5
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay
|
[PMID: 21349610] |
Chemical Information
-
CAS. Nr. 5746-27-0
-
Molecular Weight 282.26
-
Formel C10H14N6O4
-
SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC=N/C3=N\N)=C3N=C2)O1
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)