DSPE-PEG2000-Maleimide sodium (purity>98%)
Based on 2 publication(s) in Google Scholar
DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery.
For research use only. We do not sell to patients.
- Purity: 99.97%
- Molecular Weight:2000 (Average)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) DSPE-PEG2000-Maleimide sodium (purity>98%)
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Biological Activity
DSPE-PEG2000-Maleimide sodium (purity>98%) (2 mM; 12 h) successfully conjugates with one thiolated RGD peptide via Michael addition at 4°C, pH 8 to form DSPE-PEG(2000)-RGD[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 2000 (Average)
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCCC(O[C@](COP(OCCNC(OCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O[Na])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Death Dis
OSCAR functions as a collagen I receptor to suppress hippo signaling and reprogram lipid metabolism in clear-cell renal cell carcinoma. [Abstract]2026 Apr 8;17(1):499. PMID: 41951612 -
Solvent & Solubility
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Chen CW, et al. Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells. Int J Nanomedicine. 2011;6:2567-2580. [Content Brief]
[2]. Nallamothu R, et al. A tumor vasculature targeted liposome delivery system for combretastatin A4: design, characterization, and in vitro evaluation. AAPS PharmSciTech. 2006;7(2):E32. Published 2006 Apr 7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)