DSPE-PEG5000-Maleimide
Based on 4 publication(s) in Google Scholar
DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes.
For research use only. We do not sell to patients.
- Purity: 99.84%
- Molecular Weight:5000 (average)
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) DSPE-PEG5000-Maleimide
More
Customer Validation & Images
-
Bio/Physico-chemical Assay
Biological Activity
|
PEGs |
DSPE-PEG-maleimide can be coupled with thiol-p5314-29 peptide[1].
DSPE-PEG-maleimide can be used as a linker lipid in immunoliposome synthesis[2].
Sterically stabilized liposomes containing DSPE-PEG-maleimide can be coupled with thiolated monoclonal antibody OX26 (OX26-SH)[2].
HELDC liposomes prepared with 3% DSPE-PEG-maleimide shows no change in particle size over two weeks, with an average diameter of 120 nm[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Appearance Solid
-
Molecular Weight 5000 (average)
-
Color White to off-white
-
SMILES
CCCCCCCCCCCCCCCCCC(O[C@](COP(OCCNC(COCCOCCNC(CCN1C(C=CC1=O)=O)=O)=O)(O[Na])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)=O.[MW 5000].[n]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (4)
-
Journal Impact Factor
-
Most Recent
-
DSPE-PEG5000-Maleimide purchased from MedChemExpress. Usage Cited in: Compos B Eng. 2023 Oct 15, 111047.
The verification of DSPE-PEG2000-MAL-Cys-SDSSD by MALDI-TOF was performed. For the construction of BT-LGG-EVs, 1 mol Cys-SDSSD and 1 mol DSPE-PEG2000-Mal ammonium were mixed and allowed to react for 24 h to develop bone-targeting peptide DSPE-PEG-Mal-Cys-SDSSD.
-
J Tissue Eng
Cell-free osteoarthritis treatment with dual-engineered chondrocyte-targeted extracellular vesicles derived from mechanical loading primed mesenchymal stem cells. [Abstract]2025 Feb 8:16:20417314241312563. PMID: 39926048 -
-
Solvent & Solubility
DMSO : 50 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
[1]. Schnorenberg MR, et, al. Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis. ACS Omega. 2018 Oct 31;3(10):14144-14150. [Content Brief]
[2]. Huwyler J, et, al. Brain drug delivery of small molecules using immunoliposomes. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14164-9. [Content Brief]
[3]. Wholey WY, et al. Synthetic Liposomal Mimics of Biological Viruses for the Study of Immune Responses to Infection and Vaccination. Bioconjug Chem. 2020 Mar 18;31(3):685-697. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSPE-PEG5000-Maleimide Related Classifications
HY-140740 Related Classifications
Powered by Bioz