3 Results for "

epithelial barrier modulator

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "epithelial barrier modulator" in MCE Product Catalog:

Decyl β-D-maltopyranoside
Decyl β-D-maltopyranoside
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Cat. No.: HY-W040203
CAS No.: 82494-09-5
Decyl β-D-maltopyranoside is an epithelial permeability enhancer. Decyl β-D-maltopyranoside regulates the paracellular transport pathway and increases the permeability of molecules and proteins transported via the paracellular route. Decyl β-D-maltopyranoside enhances the transepithelial paracellular permeability of EPO across cell monolayers .
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Oleanolic acid 28-O-β-D-glucopyranoside
Oleanolic acid 28-O-β-D-glucopyranoside
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Cat. No.: HY-N7635
CAS No.: 14162-53-9
Synonyms: β-D-Glucopyranosyl oleanolate
Category:  

Triterpenes other families Terpenoids Other Diseases Amaranthaceae Plants Disease Research Fields Achyranthes bidentata

Target:  

NO Synthase COX Interleukin Related Claudin p38 MAPK Akt PI3K

Oleanolic acid 28-O-β-D-glucopyranoside (β-D-Glucopyranosyl oleanolate) is an orally active pentacyclic triterpenoid compound. Oleanolic acid 28-O-β-D-glucopyranoside has anti-inflammatory effects. In ulcerative colitis models, Oleanolic acid 28-O-β-D-glucopyranoside can inhibit the inflammatory response, enhance the intestinal epithelial barrier function, and modulate the gut microbiota. Its mechanism of action is related to the PI3K-AKT and MAPK signaling pathways. Oleanolic acid 28-O-β-D-glucopyranoside can be used in the research of diseases such as colitis .
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PA-IIL
PA-IIL
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Cat. No.: HY-NP216
Synonyms: LecB
PA-IIL (LecB) is a lectin produced by Pseudomonas aeruginosa. PA-IIL binds to glycosylated β1-integrin, fucose-containing glycosphingolipids, fucosylated/mannosylated neutrophil glycoconjugates, and pre-formed neutrophil extracellular traps. PA-IIL disrupts host defenses: it creates favorable conditions for Pseudomonas aeruginosa infection and dissemination by modulating the bactericidal activity of neutrophils, impairing the trafficking and recruitment of immune cells, and compromising the repair capacity of epithelial barriers. PA-IIL can be used in studies related to Pseudomonas aeruginosa infection .
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