Decyl β-D-maltopyranoside
Based on 1 Customer Validation
Decyl β-D-maltopyranoside is an epithelial permeability enhancer. Decyl β-D-maltopyranoside regulates the paracellular transport pathway and increases the permeability of molecules and proteins transported via the paracellular route. Decyl β-D-maltopyranoside enhances the transepithelial paracellular permeability of EPO across cell monolayers.
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 82494-09-5
- Formula: C22H42O11
- Molecular Weight:482.56
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Decyl β-D-maltopyranoside (0.05-0.1% (w/v); 180 min) increases paracellular transepithelial permeability of EPO across Caco-2 cell monolayers in a concentration-dependent manner, with 0.1% (w/v) elevating EPO Papp to 1.4 × 10-7 cm/s, while causing reversible monolayer tight junction changes at concentrations up to 0.1% (w/v)[1].
Decyl β-D-maltopyranoside (0.05-0.15% (w/v); 180 min) exhibits minimal cytotoxicity to Caco-2 cells at concentrations up to 0.075% (w/v) after 3-hour exposure, with 0.1% (w/v) causing reversible reduced metabolic activity and 0.15% (w/v) inducing severe cell death[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Caco-2 cells
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Concentration:0.05% (w/v); 0.075% (w/v); 0.1% (w/v); 0.15% (w/v)
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Incubation Time:3 h
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Result:Had no impact on Caco-2 cell viability after 180 min exposure, with viability remaining at ~100% of control levels.
Had no impact on Caco-2 cell viability after 180 min exposure, with viability remaining at ~100% of control levels.
Reduced cell viability to ~70% of control after 180 min exposure, with viability recovering to ~75% of control after 24 hours in fresh medium.
Caused severe toxicity, reducing viability to ~10% of control after 180 min exposure.
Chemical Information
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CAS No. 82494-09-5
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Appearance Solid
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Molecular Weight 482.56
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Formula C22H42O11
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Color White to off-white
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SMILES
O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O)[C@H](O2)CO)[C@H](O[C@H]1OCCCCCCCCCC)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
H2O : 83.33 mg/mL (172.68 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.0723 mL | 10.3614 mL | 20.7228 mL | 51.8070 mL |
| 5 mM | 0.4145 mL | 2.0723 mL | 4.1446 mL | 10.3614 mL | |
| 10 mM | 0.2072 mL | 1.0361 mL | 2.0723 mL | 5.1807 mL | |
| 15 mM | 0.1382 mL | 0.6908 mL | 1.3815 mL | 3.4538 mL | |
| 20 mM | 0.1036 mL | 0.5181 mL | 1.0361 mL | 2.5904 mL | |
| 25 mM | 0.0829 mL | 0.4145 mL | 0.8289 mL | 2.0723 mL | |
| 30 mM | 0.0691 mL | 0.3454 mL | 0.6908 mL | 1.7269 mL | |
| 40 mM | 0.0518 mL | 0.2590 mL | 0.5181 mL | 1.2952 mL | |
| 50 mM | 0.0414 mL | 0.2072 mL | 0.4145 mL | 1.0361 mL | |
| 60 mM | 0.0345 mL | 0.1727 mL | 0.3454 mL | 0.8635 mL | |
| 80 mM | 0.0259 mL | 0.1295 mL | 0.2590 mL | 0.6476 mL | |
| 100 mM | 0.0207 mL | 0.1036 mL | 0.2072 mL | 0.5181 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Decyl β-D-maltopyranoside Related Classifications
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