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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
glycolate
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "glycolate" in MCE Product Catalog:
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Lumasiran (ALN-G01), a siRNA product, reduces hepatic oxalate production by targeting glycolate oxidase. By silencing the gene encoding glycolate oxidase, Lumasiran depletes glycolate oxidase and thereby inhibits the synthesis of oxalate, which is the toxic metabolite that is directly associated with the clinical manifestations of Primary hyperoxaluria type 1 (PH1) .
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1 Cited Publications
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Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, reduces hepatic oxalate production by targeting glycolate oxidase. Lumasiran sodium reduces urinary oxalate excretion, the cause of progressive kidney failure in primary hyperoxaluria type 1 (PH1) .
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Cat. No.: HY-W088011B
CAS No.: 2836-32-0
Synonyms: Sodium hydroxyacetate, 98%
Cat. No.: HY-P10277
CAS No.: 2222514-07-8
Synonyms: Transcon PTH; ACP-014
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Cat. No.: HY-W176012
CAS No.: 330977-65-6
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Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1) .
Cat. No.: HY-22166
CAS No.: 77529-42-1
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Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.
Cat. No.: HY-P4063
CAS No.: 1350661-05-0
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Cat. No.: HY-148610
CAS No.: 893739-96-3
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LDH-IN-2, a salicylic acid derivative, is an inhibitor of glycolate oxidase (GO). LDH-IN-2 decreases oxalate output in hyperoxaluric hepatocytes. LDH-IN-2 can be used for research of primary hyperoxaluria type 1 (PH1) .
Cat. No.: HY-P10378
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Cat. No.: HY-P6959
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Cat. No.: HY-P6960
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Cat. No.: HY-156648
CAS No.: 2408241-62-1
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Vamagloxistat is glycolate oxidase inhibitor, used to inhibit hyperoxaluria and kidney stones .
Synonyms: Drosophilin B (Standard); Mutilin 14-glycolate (Standard)
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Ribulose bisphosphate carboxylase (Ribulose 1,5-bisphosphate carboxylase) catalyses the carboxylation (CO2 addition) or oxygenation (O2 addition) of d-ribulose-1,5-bisphosphate (RuBP) and the subsequent carbon–carbon cleavage to form two molecules of 3-phospho-d-glycerate (PGA) (with CO2) or one molecule of PGA and one molecule of 2-phospho-glycolate (PG; with O2) .
Cat. No.: HY-156648A
CAS No.: 2667602-26-6
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Vamagloxistat (sodium) is glycolate oxidase inhibitor, used to inhibit hyperoxaluria and kidney stones .
Cat. No.: HY-E70953
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Pyruvate Kinase/Lactic Dehydrogenase enzymes, Rabbit catalyzes an ATP-dependent phosphorylation of glycolate to yield 2-phosphoglycolate. Pyruvate kinase requires bivalent and monovalent cations such as Mg 2+ and K + respectively for activation to occur.
Cat. No.: HY-P70932
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HAO1; glycolate Oxidase 1; Prev. GOX1; HAOX1; GOX; GO; Hydroxyacid Oxidase (glycolate Oxidase) 1; Alternative Protein HAO1; (S)-2-Hydroxy-Acid Oxidase; glycolate Oxidase; 2-Hydroxyacid Oxidase 1; Hydroxyacid Oxidase 1; Glyoxylate Oxidase
Cat. No.: HY-P71655
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HAO1; glycolate Oxidase 1; Prev. GOX1; HAOX1; GOX; GO; Hydroxyacid Oxidase (glycolate Oxidase) 1; Alternative Protein HAO1; (S)-2-Hydroxy-Acid Oxidase; glycolate Oxidase; 2-Hydroxyacid Oxidase 1; Hydroxyacid Oxidase 1; Glyoxylate Oxidase
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
