Glycolate oxidase-IN-1
Glycolate oxidase-IN-1(compound 26), a salicylic acid derivative, is a glycolate oxidase (GO) inhibitor with an IC50 of 38.2 μM. Glycolate oxidase-IN-1 has the ability to reduce oxalate production in hyperoxalate hepatocytes and can be used in the study of primary hyperoxaluria type 1 (PH1).
For research use only. We do not sell to patients.
- CAS No.: 330977-65-6
- Formula: C12H8O5
- Molecular Weight:232.19
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Glycolate oxidase-IN-1(compound 26)(0-12.5 μM, 48 h) treated mouse hepatocytes, at a concentration of 6.25 μM, the level of excreted oxalate is significantly reduced by 67.3 ± 32%. At a concentration of 12.5 μM, the reduction is 105.8 ± 29.2% and 62.3 ± 24.4% after 24 and 48 hours of treatment, respectively, without any cytotoxicity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 330977-65-6
-
Molecular Weight 232.19
-
Formula C12H8O5
-
SMILES
O=C(O)C1=CC(C2=CC=C(C=O)O2)=CC=C1O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glycolate oxidase-IN-1 Related Classifications
HY-W176012 Related Classifications
Powered by Bioz