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Glycolic acid oxidase inhibitor 1 

Cat. No.: HY-22166 Purity: 98.91%
COA Handling Instructions

Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.

For research use only. We do not sell to patients.

Glycolic acid oxidase inhibitor 1 Chemical Structure

Glycolic acid oxidase inhibitor 1 Chemical Structure

CAS No. : 77529-42-1

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 132 In-stock
Solution
10 mM * 1 mL in DMSO USD 132 In-stock
Solid
5 mg USD 120 In-stock
10 mg USD 180 In-stock
50 mg USD 540 In-stock
100 mg USD 810 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.

IC50 & Target

Glycolate oxidase[1]

In Vivo

Glycolic acid oxidase inhibitor 1 inhibits oxalate biosynthesis in isolated perfused rat liver. Glycolate oxidase inhibitors provide a specific approach to the prevention and treatment of calcium oxalate renal lithiasis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

344.16

Formula

C16H10BrNO3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C(C1=CC=C(C2=CC=C(Br)C=C2)C=C1)=C3O)NC3=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 137 mg/mL (398.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9056 mL 14.5281 mL 29.0563 mL
5 mM 0.5811 mL 2.9056 mL 5.8113 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9056 mL 14.5281 mL 29.0563 mL 72.6406 mL
5 mM 0.5811 mL 2.9056 mL 5.8113 mL 14.5281 mL
10 mM 0.2906 mL 1.4528 mL 2.9056 mL 7.2641 mL
15 mM 0.1937 mL 0.9685 mL 1.9371 mL 4.8427 mL
20 mM 0.1453 mL 0.7264 mL 1.4528 mL 3.6320 mL
25 mM 0.1162 mL 0.5811 mL 1.1623 mL 2.9056 mL
30 mM 0.0969 mL 0.4843 mL 0.9685 mL 2.4214 mL
40 mM 0.0726 mL 0.3632 mL 0.7264 mL 1.8160 mL
50 mM 0.0581 mL 0.2906 mL 0.5811 mL 1.4528 mL
60 mM 0.0484 mL 0.2421 mL 0.4843 mL 1.2107 mL
80 mM 0.0363 mL 0.1816 mL 0.3632 mL 0.9080 mL
100 mM 0.0291 mL 0.1453 mL 0.2906 mL 0.7264 mL
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Glycolic acid oxidase inhibitor 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Glycolic acid oxidase inhibitor 1
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