Search Result

Results for "

gonadotropin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	GnRH Receptor (60) Amino Acid Derivatives (2) Apoptosis (7) Biochemical Assay Reagents (1) Dopamine Receptor (3) Drug Derivative (1) Endogenous Metabolite (3) Environmental Pollutants (1) Estrogen Receptor/ERR (4) Fluorescent Dye (1) Glutathione S-transferase (1) Isotope-Labeled Compounds (7) Kisspeptin Receptor (2) MDM-2/p53 (1) Neurokinin Receptor (1) Neuropeptide FF Receptor (1) Neuropeptide Y Receptor (3) Nuclear Factor of activated T Cells (NFAT) (6) PERK (1) PPAR (1) Progesterone Receptor (1) Ras (1) Reference Standards (5) TSH Receptor (2)
By Research Areas:	Cancer (31) Cardiovascular Disease (1) Endocrinology (54) Inflammation/Immunology (4) Metabolic Disease (8) Neurological Disease (10)

By Targets:

GnRH Receptor (60)

Amino Acid Derivatives (2)

Apoptosis (7)

Biochemical Assay Reagents (1)

Dopamine Receptor (3)

Drug Derivative (1)

Endogenous Metabolite (3)

Environmental Pollutants (1)

Estrogen Receptor/ERR (4)

Fluorescent Dye (1)

Glutathione S-transferase (1)

Isotope-Labeled Compounds (7)

Kisspeptin Receptor (2)

MDM-2/p53 (1)

Neurokinin Receptor (1)

Neuropeptide FF Receptor (1)

Neuropeptide Y Receptor (3)

Nuclear Factor of activated T Cells (NFAT) (6)

PERK (1)

PPAR (1)

Progesterone Receptor (1)

Ras (1)

Reference Standards (5)

TSH Receptor (2)

By Research Areas:

Cancer (31)

Cardiovascular Disease (1)

Endocrinology (54)

Inflammation/Immunology (4)

Metabolic Disease (8)

Neurological Disease (10)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: GnRH Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16168A

Degarelix Maximum Cited Publications 11 Publications Verification FE 200486 free base	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC₅₀ = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer .

HY-107953

Chorionic gonadotrophin 3 Publications Verification hCG; Chorionic gonadotropic hormone	Endogenous Metabolite	Endocrinology Cancer
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-13673A

Goserelin acetate 1 Publications Verification ICI-118630 acetate	GnRH Receptor Apoptosis	Endocrinology Cancer
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-16474

Relugolix TAK-385	GnRH Receptor	Endocrinology Cancer
Relugolix (TAK-385)?is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC₅₀=0.33 nM) and monkey receptor (IC₅₀=0.32 nM) compared with TAK-013 (HY-100209) . Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al .

HY-N12634

Pregnant mare serum gonadotropin PMSG	Endogenous Metabolite	Endocrinology
Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .

HY-P0009A

Cetrorelix Acetate 1 Publications Verification SB-75 acetate	GnRH Receptor	Neurological Disease Endocrinology
Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC₅₀ of 1.21 nM .

HY-14369

Elagolix sodium NBI-56418 sodium	GnRH Receptor Nuclear Factor of activated T Cells (NFAT)	Metabolic Disease Cancer
Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .

HY-14789

(R)-Elagolix NBI-56418	GnRH Receptor Nuclear Factor of activated T Cells (NFAT)	Endocrinology Cancer
Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .

HY-106279

EA-230	GnRH Receptor	Inflammation/Immunology
EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis .

HY-P3582

sGnRH-A	GnRH Receptor	Endocrinology
sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .

HY-B1904

Fluphenazine decanoate	Dopamine Receptor	Neurological Disease
Fluphenazine decanoate is a CNS-penetrant dopamine D₂ receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .

HY-P1628

Ganirelix	GnRH Receptor	Metabolic Disease
Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea .

HY-P1022

Kisspeptin-54(human) 3 Publications Verification Metastin(human)	GnRH Receptor	Endocrinology Cancer
Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with K_i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone .

HY-P0243

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH	GnRH Receptor	Metabolic Disease
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

HY-P0051

Lecirelin 2 Publications Verification	GnRH Receptor	Endocrinology Cancer
Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .

HY-16027

Acyline	GnRH Receptor	Endocrinology
Acyline, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-133080

BAY-784	GnRH Receptor	Cancer
BAY-784 is a gonadotropin releasing hormone receptor (GnRH-R) antagonist probe with IC₅₀s of 21 and 24 nM for human and rat GnRH-R, respectively .

HY-100271

Org41841	TSH Receptor	Endocrinology
Org41841 is a partial agonist of both luteinizing hormone/chorionic gonadotropin receptor (LHCGR) and thyroid-stimulating hormone receptor (TSHR) with EC₅₀s of 0.2 and 7.7 μM, respectively.

HY-W041308

DCOIT Kathon 930	Environmental Pollutants GnRH Receptor	Endocrinology
DCOIT is a representative isothiazolinone that stimulates the gonadotropin-releasing hormone receptor (GnRHR)-mediated synthesis of follicle-stimulating hormone and luteinizing hormone in the brain. DCOIT interferes with G protein-coupled receptors, MAPK and Ca ²⁺ signaling cascades .

HY-109532

Ganirelix acetate Ganirest	GnRH Receptor	Metabolic Disease
Ganirelix acetate (Ganirest) is a competitive and selective gonadotropin-releasing hormone (GnRH) antagonist. Ganirelix acetate blocks endogenous GnRH-induced release of luteinizing hormone (LH) and follicle-stimulating hormone. Ganirelix acetate antagonizes Prostaglandin E2 (HY-101952)-induced detrusor overactivity and enhances Carbachol (HY-B1208)-induced detrusor contraction. Ganirelix acetate is applicable to research related to female infertility and detrusor overactivity .

HY-W009066

2-Ethylhexyl diphenyl phosphate EHDPP; Octicizer	PPAR Progesterone Receptor Estrogen Receptor/ERR	Endocrinology
2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC₂₀: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC₅₀: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, *human chorionic gonadotropin* (hCG) and progesterone** secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development .

HY-P0048

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH 1 Publications Verification Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

HY-P1428

RFRP-1(human) 1 Publications Verification	Neuropeptide Y Receptor	Endocrinology
RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits *gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2* and NPFF1, respectively .

HY-P10419

Zebrafish Kisspeptin-1	Kisspeptin Receptor GnRH Receptor	Endocrinology
Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system .

HY-13673

Goserelin ICI 118630	GnRH Receptor Apoptosis	Endocrinology Cancer
Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-P1250

RFRP-3(human) Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human)	Neuropeptide Y Receptor	Neurological Disease
RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca ²⁺ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC₅₀ of 0.7 nM .

HY-16168

Degarelix acetate FE 200486	GnRH Receptor	Cancer
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC₅₀ = 3 nM). Degarelix acetate (FE 200486) is used for the research of prostate cancer .

HY-P3862

[MePhe7]-Neurokinin B	Neurokinin Receptor	Neurological Disease Endocrinology
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC₅₀ value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R) .

HY-P3605

GnRH Associated Peptide (25-53), human GAP (25-53), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-164032

Dimethandrolone undecanoate 7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate	GnRH Receptor	Endocrinology
Dimethandrolone undecanoate (7α,11β-Dimethyl-17β-hydroxyestr-4-en-3-one 17-undecanoate) exhibits withrogens and progesterone activity. Dimethandrolone undecanoate inhibits production of gonadotropins, suppresses testosterone production, and thus inhibits sperm production. Dimethandrolone undecanoate is potent for development of male hormone contraceptives .

HY-16027A

Acyline TFA	GnRH Receptor	Endocrinology
Acyline TFA, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-P11278

Federelin Gonadorelin[6-D-Phe]; [D-Phe6]GnRH	GnRH Receptor	Endocrinology
Federelin (Gonadorelin[6-D-Phe]) is a gonadotropin (GnRH) analog .

HY-P0009B

Cetrorelix diacetate SB-75 diacetate	GnRH Receptor	Neurological Disease Endocrinology
Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC₅₀ of 1.21 nM .

HY-P3582A

sGnRH-A acetate	GnRH Receptor	Endocrinology
sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination .

HY-P3666

[D-Phe2,6, Pro3]-LH-RH	GnRH Receptor	Endocrinology
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .

HY-13673S2

Goserelin-d7 TFA ICI 118630-d7 TFA	Isotope-Labeled Compounds Apoptosis GnRH Receptor	Endocrinology Cancer
Goserelin-d₇ (TFA) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-144863

BAY 1214784	GnRH Receptor	Cancer
BAY 1214784 is a potent, selective, and orally active antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R). BAY 1214784 is a spiroindoline derivative compound. BAY 1214784 effectively lowers plasma luteinizing hormone levels by up to 49%, at the same time being associated with low pharmacokinetic variability and good tolerability. BAY 1214784 has the potential for the research of uterine fibroids .

HY-16474R

Relugolix (Standard) TAK-385 (Standard)	Reference Standards GnRH Receptor	Endocrinology Cancer
Relugolix (Standard) is the analytical standard of Relugolix. This product is intended for research and analytical applications. Relugolix (TAK-385) is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC₅₀=0.33 nM) and monkey receptor (IC₅₀=0.32 nM) compared with TAK-013 (HY-100209) . Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al .

HY-B1904A

Fluphenazine decanoate dihydrochloride	Dopamine Receptor	Neurological Disease
Fluphenazine decanoate dihydrochloride is a CNS-penetrant dopamine D₂ receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research .

HY-P3084

*Human follicular gonadotropin* releasing peptide** hF-GRP	GnRH Receptor	Endocrinology
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .

HY-120767

Linzagolix choline KLH-2109 choline; OBE-2109 choline	GnRH Receptor	Inflammation/Immunology Cancer
Linzagolix choline (KLH-2109 choline) is a non-peptide gonadotropin-releasing hormone (GnRH) antagonist with oral activity. Linzagolix choline inhibits the release of endogenous gonadotropins such as luteinizing hormone LH and follicle-stimulating hormone FSH by binding to the GnRH receptor within the pituitary gland. This inhibition results in a reduction in the production of sex hormones such as estrogen and progesterone, which in turn affects the course of sex hormone-dependent diseases. Linzagolix choline can be used in the study of sex hormone-dependent diseases such as endometriosis and uterine fibroids .

HY-P1022A

Kisspeptin-54(human) TFA 3 Publications Verification Metastin(human) TFA	GnRH Receptor	Endocrinology Cancer
Kisspeptin-54(human) TFA (Metastin(human) TFA) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) TFA binds to rat and human GPR54 receptors with K_i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) TFA hinders tumor metastasis and stimulates gonadotropin secretion .

HY-178419

GnRH-R antagonist-3	GnRH Receptor	Cancer
GnRH-R antagonist-3 (Compound 37) is a Gonadotropin releasing hormone receptor (GnRH-R) antagonist with IC₅₀s of 94 and 275 nM for rat and human GnRH-R, respectively. GnRH-R antagonist-3 can be used for hormone dependent diseases such as endometriosis, breast and prostate cancer research .

HY-U00289

Opigolix ASP-1707	GnRH Receptor	Inflammation/Immunology Endocrinology
Opigolix (ASP-1707) is a Gonadotropin-releasing hormone (GnRH) receptor antagonist, used for the research of endometriosis and rheumatoid arthritis.

HY-16168B

Degarelix acetate hydrate FE 200486 acetate hydrate	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate hydrate (FE 200486 acetate hydrate) is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research .

HY-P1905

[Gln8]-C517 (LH-RH), chicken	GnRH Receptor	Endocrinology
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

HY-W554614

Diethylstilbestrol diphosphate Fosfestrol	Estrogen Receptor/ERR	Cancer
Diethylstilbestrol diphosphate (Fosfestrol) is a diphosphate of diethylstilbestrol and an agonist of estrogen receptors. Diethylstilbestrol diphosphate is a prodrug of diethylstilbestrol and has a powerful anti-gonadotropin effect. Diethylstilbestrol diphosphate can be used in the research of prostate cancer .

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P2082

[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH	GnRH Receptor	Others
[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH is a gonadotropin-releasing hormone (Gn-RH) agonist that has a dose-dependent inhibitory activity on progesterone secretion from cultured human granulosa cells.

HY-P3664

[D-Phe2,D-Ala6]-LH-RH Wy 18185	GnRH Receptor	Endocrinology
[D-Phe2,D-Ala6]-LH-RH is a potent LH-RH antagonist. [D-Phe2,D-Ala6]-LH-RH shows anti-LH/FSH-RH and antiovulatory activities .

Cat. No.	Product Name	Target	Research Area

HY-16168A

Degarelix Maximum Cited Publications 11 Publications Verification FE 200486 free base	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC₅₀ = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer .

HY-13673A

Goserelin acetate 1 Publications Verification ICI-118630 acetate	GnRH Receptor Apoptosis	Endocrinology Cancer
Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-P0009A

Cetrorelix Acetate 1 Publications Verification SB-75 acetate	GnRH Receptor	Neurological Disease Endocrinology
Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC₅₀ of 1.21 nM .

HY-106279

EA-230	GnRH Receptor	Inflammation/Immunology
EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis .

HY-P3582

sGnRH-A	GnRH Receptor	Endocrinology
sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .

HY-P1628

Ganirelix	GnRH Receptor	Metabolic Disease
Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea .

HY-P1022

Kisspeptin-54(human) 3 Publications Verification Metastin(human)	GnRH Receptor	Endocrinology Cancer
Kisspeptin-54(human) (Metastin(human)) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) binds to rat and human GPR54 receptors with K_i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) inhibits tumor metastasis and stimulates the secretion of gonadotropin (LH) and testosterone .

HY-P0243

Luteinizing Hormone Releasing Hormone (LH-RH), salmon Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH	GnRH Receptor	Metabolic Disease
Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.

HY-P0051

Lecirelin 2 Publications Verification	GnRH Receptor	Endocrinology Cancer
Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .

HY-16027

Acyline	GnRH Receptor	Endocrinology
Acyline, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-P0048

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH 1 Publications Verification Surfagon	GnRH Receptor	Others
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .

HY-P1428

RFRP-1(human) 1 Publications Verification	Neuropeptide Y Receptor	Endocrinology
RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits *gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2* and NPFF1, respectively .

HY-P10419

Zebrafish Kisspeptin-1	Kisspeptin Receptor GnRH Receptor	Endocrinology
Zebrafish Kisspeptin-1 is the core sequence of the neuropeptide kisspeptin-1, which participate in the regulation of gonadotropin-releasing hormone (GnRH) release, and regulates the reproductive system .

HY-13673

Goserelin ICI 118630	GnRH Receptor Apoptosis	Endocrinology Cancer
Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-P1250

RFRP-3(human) Neuropeptide VF(124-131)(human); Neuropeptide NPVF (human)	Neuropeptide Y Receptor	Neurological Disease
RFRP-3 (Neuropeptide VF(124-131))(human), a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca ²⁺ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC₅₀ of 0.7 nM .

HY-P3862

[MePhe7]-Neurokinin B	Neurokinin Receptor	Neurological Disease Endocrinology
[MePhe7]-Neurokinin B is an neurokinin NK-3 receptor (NK3R) agonist with an IC₅₀ value of 3 nM. [MePhe7]-Neurokinin B is a potential regulator of pulsatile gonadotropin-releasing hormone (GnRH) secretion via activation of the neurokinin-3 receptor (NK3R) .

HY-P3605

GnRH Associated Peptide (25-53), human GAP (25-53), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (25-53), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 25-53 fragment (hGAP-25-53), can be used as immunogen to generate antiseras including MC-1, MC-2, and MC-3. GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-16027A

Acyline TFA	GnRH Receptor	Endocrinology
Acyline TFA, a GnRH peptide analogue, is a GnRH antagonist that inhibits gonadotropin and testosterone (T) levels .

HY-P11278

Federelin Gonadorelin[6-D-Phe]; [D-Phe6]GnRH	GnRH Receptor	Endocrinology
Federelin (Gonadorelin[6-D-Phe]) is a gonadotropin (GnRH) analog .

HY-P0009B

Cetrorelix diacetate SB-75 diacetate	GnRH Receptor	Neurological Disease Endocrinology
Cetrorelix diacetate (SB-075 diacetate) is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist with an IC₅₀ of 1.21 nM .

HY-P3582A

sGnRH-A acetate	GnRH Receptor	Endocrinology
sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination .

HY-P3666

[D-Phe2,6, Pro3]-LH-RH	GnRH Receptor	Endocrinology
[D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .

HY-P3084

*Human follicular gonadotropin* releasing peptide** hF-GRP	GnRH Receptor	Endocrinology
Human follicular gonadotropin releasing peptide (hF-GRP) is a hormone peptide. Human follicular gonadotropin releasing peptide can stimulate pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion in vitro .

HY-P11196

Allatostatin C AstC	Peptides	Neurological Disease Metabolic Disease
Allatostatin C (AstC) is a neuropeptide that suppresses gonadotropin production. Allatostatin C generates oogenesis rhythm by regulating juvenile hormone and vitellogenesis indirectly via insulin signaling. Allatostatin C can be used for neurological research .

HY-P1022A

Kisspeptin-54(human) TFA 3 Publications Verification Metastin(human) TFA	GnRH Receptor	Endocrinology Cancer
Kisspeptin-54(human) TFA (Metastin(human) TFA) is an endogenous ligand for kisspeptin receptor (KISS1, GPR54). Kisspeptin-54(human) TFA binds to rat and human GPR54 receptors with K_i values of 1.81 nM and 1.45 nM, respectively. Kisspeptin-54(human) TFA hinders tumor metastasis and stimulates gonadotropin secretion .

HY-16168B

Degarelix acetate hydrate FE 200486 acetate hydrate	GnRH Receptor Apoptosis	Endocrinology Cancer
Degarelix acetate hydrate (FE 200486 acetate hydrate) is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR/LHRHR) antagonist. Degarelix acetate hydrate can be used for prostate cancer research .

HY-P4904

RFRP-3 (rat) Neuropeptide NPVF (rat)	Peptides	Neurological Disease
RFRP-3 (rat) is a neuropeptide. RFRP-3 (rat) inhibits gonadotropin secretion, causing a marked increase in ghrelin mRNA and plasma growth hormone levels .

HY-P1905

[Gln8]-C517 (LH-RH), chicken	GnRH Receptor	Endocrinology
[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

HY-P10472

Azaline B	GnRH Receptor	Endocrinology
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC₅₀ of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .

HY-P2082

[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH	GnRH Receptor	Others
[D-pGlu1,D-Phe2,D-NaI3,6]-Gn-RH is a gonadotropin-releasing hormone (Gn-RH) agonist that has a dose-dependent inhibitory activity on progesterone secretion from cultured human granulosa cells.

HY-P3664

[D-Phe2,D-Ala6]-LH-RH Wy 18185	GnRH Receptor	Endocrinology
[D-Phe2,D-Ala6]-LH-RH is a potent LH-RH antagonist. [D-Phe2,D-Ala6]-LH-RH shows anti-LH/FSH-RH and antiovulatory activities .

HY-P11265

YQGN-7	GnRH Receptor Fluorescent Dye	Cancer
YQGN-7 is a targeted fluorescent probe for the gonadotropin-releasing hormone receptor (RnRHR). YQGN-7 exhibits high selectivity and affinity for breast cancer cells (K_D = 217.8 nM). YQGN-7 achieves precise visualization of the primary and metastatic lesions of breast cancer by targeting the highly expressed GnRHR in tumor cells. YQGN-7 can be used in the research of breast cancer breast-conserving surgery (BCS) .

HY-P10780

RFRP-3 (mouse) Neuropeptide NPVF (mouse)	Neuropeptide FF Receptor Apoptosis MDM-2/p53 PERK	Endocrinology
RFRP-3 (mouse) is a functional ortholog of avian gonadotropin inhibitory hormone (GnIH), binding to GPR147. RFRP-3 (mouse) reduces Progesterone synthesis by inhibiting FSHR and key enzymes involved in steroidogenesis (P450scc, 3β-HSD, StAR). RFRP-3 (mouse) induces Apoptosis (increase of p53). RFRP-3 (mouse) also suppresses the ERK signaling pathway. RFRP-3 (mouse) can be used for research of follicular development .

HY-W044285

Fmoc-D-4-Aph(cBm)-OH	Amino Acid Derivatives	Others
Fmoc-D-4-Aph(cBm)-OH is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize biologically active peptide mimetics, such as Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph/4Amf(P)-D4Aph/D4Amf(Q)-Leu-ILys-Pro-DAla-NH2 with gonadotropin-releasing hormone (GnRH) antagonist activity .

HY-P2446

ORG 30276 APTAA-LHRH	GnRH Receptor	Endocrinology
ORG 30276 (APTAA-LHRH) is a potent GnRH antagonist that effectively reduces serum LH and FSH levels in male rats. ORG 30276 significantly decreases unoccupied pituitary GnRH receptors, leading to suppressed gonadotropin secretion. ORG 30276 treatment results in a considerable reduction in mRNA levels of gonadotropin beta-subunits in the pituitary gland. ORG 30276's effects on gonadotropin dynamics can be selectively reversed by the replacement of specific sex steroids, with androgens being particularly effective for the FSH beta-subunit mRNA levels.

HY-106138

Avorelin Meterelin; MF 6001	GnRH Receptor	Cancer
Avorelin (Meterelin) is a gonadotropin releasing hormone (GnRH) agonist. Avorelin can be used of the study of prostate cancer .

HY-P1414

Canine KP-10	Kisspeptin Receptor	Endocrinology
Canine KP-10 is a potent kisspeptin that elicits strong gonadotropin and estradiol responses in female dogs in estrus .

HY-P4759

(D-His2)-Goserelin	GnRH Receptor	Others
(D-His2)-Goserelin is a derivative of Goserelin, a decapeptide analog of gonadotropin-releasing hormone (GnRH/LHRH) .

HY-P3673

Lamprey LH-RH I	GnRH Receptor	Endocrinology
Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .

HY-W006937

Boc-D-(4-fmoc)-aminophenylalanine Boc-p-amino-D-Phe(Fmoc)-OH; Boc-D-phe(4-NH-fmoc)-OH	Amino Acid Derivatives	Others
Boc-D-(4-fmoc)-aminophenylalanine (Boc-p-amino-D-Phe(Fmoc)-OH) is an amino acid derivative with an Fmoc protecting group, which can be used to synthesize peptides with gonadotropin-releasing hormone antagonist activity .

HY-P3606

GnRH Associated Peptide (1-24), human GAP (1-24), human	GnRH Receptor	Endocrinology
GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site .

HY-P10594

Myr-Arf1(2–17)	Ras	Endocrinology
Myr-Arf1(2–17) is a sarcosinated peptide that mimics the localization and function of Arf1 protein on the cell membrane. Myr-Arf1(2–17) can be used to study the desensitization mechanism of luteinizing hormone/chorionic gonadotropin receptor (LH/CGR) .

HY-P3317

Azaline Azaline A	GnRH Receptor	Endocrinology
Azaline (Azaline A) is a gonadotropin-releasing hormone (GnRH) receptor antagonist with a K_D value of 0.48 nM. Azaline can effectively induce histamine release, with an effect comparable to that of GnRH, and it can completely inhibit ovulation at a dose of 2.0-3.0 μg per female rat. Azaline has potential applications in regulating reproductive functions .

HY-P1250A

RFRP-3(human) TFA Neuropeptide VF(124-131)(human) TFA; Neuropeptide NPVF (human) TFA	Neuropeptide Y Receptor	Neurological Disease
RFRP-3 (Neuropeptide VF(124-131))(human) TFA, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca ²⁺ mobilization. RFRP-3(human) is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC₅₀ of 0.7 nM .

HY-P11181

*Chorionic Gonadotropin-beta (109-145) (human)* hCGβ (109–145)	GnRH Receptor	Inflammation/Immunology
Chorionic Gonadotropin-beta (109-145) (human) is the carboxyl-terminal part (109-145) of the human chorionic gonadotropin beta subunit. Chorionic Gonadotropin-beta (109-145) (human) can be used in the research of immune responses .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-107953

Chorionic gonadotrophin 3 Publications Verification hCG; Chorionic gonadotropic hormone	Natural Products Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Endogenous Metabolite
Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development .

HY-N12634

Pregnant mare serum gonadotropin PMSG	Natural Products Animals Source Classification	Endogenous Metabolite
Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .

HY-119332

3-Keto petromyzonol	Animals Classification of Application Fields Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite
3-Keto petromyzonol, a main component of Sea lamprey male sex pheromones, modulates both synthesis and release of gonadotropin releasing hormone (GnRH), and subsequently, hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey .

Species:	Human (1) Rhesus Macaque (1)
Tag:	His (2)
Source:	HEK293 (1) E. coli Cell-free (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P702298

	GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) gonadotropin-releasing hormone II receptor; Type II GnRH receptor	Rhesus Macaque	E. coli Cell-free
	The GNRHR2 Protein serves as a receptor for gonadotropin-releasing hormone II (GnRH II), initiating its action through association with G proteins that activate a phosphatidylinositol-calcium second messenger system. GNRHR2 Protein, Rhesus Macaque (Cell-Free, His) is the recombinant Rhesus Macaque-derived GNRHR2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

HY-P70205

	Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) rHuProgonadoliberin-2/GnRH II, His; Progonadoliberin-2; Progonadoliberin II; Gonadoliberin-2; Gonadoliberin II; gonadotropin-Releasing Hormone II; GnRH II; Luliberin II; Luteinizing Hormone-Releasing Hormone II; LH-RH II; GnRH-Associated Peptide 2; GnRH-Associated Peptide II; GNRH2	Human	HEK293
	Progonadoliberin-2/GNRH II Proteinas, a pivotal player in the endocrine system, potently stimulates gonadotropin secretion, promoting both luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release. Its capacity to orchestrate the secretion of these hormones underscores its significance in governing reproductive functions within the intricate endocrine signaling network that regulates the reproductive axis. Progonadoliberin-2/GNRH II Protein, Human (HEK293, His) is the recombinant human-derived Progonadoliberin-2/GNRH II protein, expressed by HEK293 , with C-6*His labeled tag.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name	Chemical Structure

HY-13673S2

Goserelin-d7 TFA
Goserelin-d₇ (TFA) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-16474S

Relugolix-d6

Relugolix-d₆ is deuterium labeled Relugolix. Relugolix (TAK-385)?is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC₅₀=0.33 nM) and monkey receptor (IC₅₀=0.32 nM) compared with TAK-013 (HY-100209) . Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al .

HY-16168AS

Degarelix-d7
Degarelix-d₇ (FE 200486-d₇ free base) is deuterium labeled Degarelix. Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.

HY-13673S1

Goserelin-d7
Goserelin-d₇ (ICI 118630-d₇) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-13673S

Goserelin-d10
Goserelin-d₁₀ (ICI 118630-d₁₀) is deuterium labeled Goserelin. Goserelin (ICI 118630), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .

HY-W751574

Elagolix-d6 sodium
Elagolix-d₆ (sodium) (NBI-56418-d₆ (sodium)) is deuterium labeled Elagolix sodium. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .

HY-115633S

Elagolix-d9
Elagolix-d₉ is the deuterium labeled Elagolix. Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .

Host:	Mouse (1) Rabbit (1)
Reactivity:	Human (2)
Application:	IHC-P (2) ICC/IF (1) ELISA (1)
Isotype:	IgG (1) IgG1,IgG/Kappa (1)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86051

	hCG beta Antibody (YA5743) CG beta; CG-beta; CgB; CGB3; CGB3_HUMAN; CGB5; CGB7; CGB7_HUMAN; CGB8; CGHB_HUMAN; Choriogonadotropin subunit beta 3; Choriogonadotropin subunit beta 7; Choriogonadotropin subunit beta; Chorionic gonadotropin beta polypeptide; Chorionic gonadotropin chain beta	IHC-P, ICC/IF, ELISA	Human
	hCG beta Antibody (YA5743) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to hCG beta.

HY-P87160

	hCG beta Antibody (YA6853) CG beta antibody; CG-beta antibody; CgB antibody; CGB3 antibody; CGB3_HUMAN antibody; CGB5 antibody; CGB7 antibody; CGB7_HUMAN antibody; CGB8 antibody; CGHB_HUMAN antibody; CG beta antibody; CG-beta antibody; CgB antibody; CGB3 antibody; CGB3_HUMAN antibody; CGB5 antibody; CGB7 antibody; CGB7_HUMAN antibody; CGB8 antibody; CGHB_HUMAN antibody; Choriogonadotropin subunit beta 3 antibody; Choriogonadotropin subunit beta 7 antibody; Choriogonadotropin subunit beta antibody; Chorionic gonadotropin beta polypeptide antibody; Chorionic gonadotropin chain beta antibody;	IHC-P	Human
	hCG beta Antibody (YA6853) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to hCG beta.