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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
34 Results for "
malonyl-CoA
" in MedChemExpress (MCE) Product Catalog:
Products (34)
34 Results for "malonyl-CoA" in MCE Product Catalog:
11
11 Publications Verification
Target:
Áreas de investigación:
CP-640186 is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 can also stimulate muscle fatty acid oxidation .
11
11 Publications Verification
Target:
Áreas de investigación:
CP-640186 hydrochloride is an orally active and cell-permeable Acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. Acetyl-CoA carboxylase (ACC) is a key enzyme of fatty acid metabolism that enables the synthesis of malonyl-CoA. CP-640186 hydrochloride can also stimulate muscle fatty acid oxidation .
2
2 Cited Publications
Synonyms: malonyl coenzyme A lithium
Áreas de investigación:
Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation .
1
1 Cited Publications
Referencia número: HY-P71828
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MCAT; malonyl-CoA-Acyl Carrier Protein Transacylase, Mitochondrial; malonyl-CoA-Acyl Carrier Protein Transacylase; malonyl CoA:ACP Acyltransferase (Mitochondrial); MCT; Mitochondrial malonyl CoA:ACP Acyltransferase; MT; [Acyl-Carrier-Protein] S-malonyltra
Species:
Source:
Target:
Áreas de investigación:
ELOVL6-IN-1 is a potent, orally active and selective ELOVL6 inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse ELOVL6 activities, with an IC50 value of 0.350 μM. ELOVL6-IN-1 inhibits ELOVL6 in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA .
Referencia número: HY-B2013
No. CAS: 71283-80-2
Target:
Áreas de investigación:
Fenoxaprop-P-ethyl is an acetyl-CoA carboxylase (ACC) inhibitor and post-emergence herbicide. Fenoxaprop-P-ethyl inhibits the conversion of acetyl-CoA to malonyl-CoA, reduces malonyl-CoA synthesis and disrupts fatty acid synthesis. Fenoxaprop-P-ethyl disrupts lipid homeostasis through cascaded inhibition of lipid metabolism, decreases total lipid content, downregulates fatty acid elongase genes and inhibits their activity. Fenoxaprop-P-ethyl disrupts fatty acid synthesis in rice seedlings and controls annual monocotyledonous weeds in wheat, durum wheat, rye, triticale and barley fields .
Referencia número: HY-W012865
No. CAS: 80-69-3
Áreas de investigación:
Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research .
Referencia número: HY-N9686
No. CAS: 53034-79-0
Category:
Target:
Referencia número: HY-B2007
No. CAS: 79241-46-6
Áreas de investigación:
Fluazifop-P-butyl is an orally active herbicide and ACCase inhibitor. Fluazifop-P-butyl blocks the formation of malonyl-CoA, disrupts lipid synthesis in sensitive plants, and exhibits concentration-dependent phytotoxicity to non-target maize seedlings. Fluazifop-P-butyl induces oxidative stress in male Wistar rats, impairs their liver and kidney functions, and disrupts testicular function .
Referencia número: HY-141473
No. CAS: 116928-84-8
Synonyms: malonyl coenzyme A tetralithium
Referencia número: HY-179170S
Synonyms: malonyl coenzyme A-13C3 lithium
Referencia número: HY-113499B
Target:
Áreas de investigación:
cis-Malonylcarnitine lithium is an ester compound and a metabolite of Malonyl CoA (HY-115899). The level of cis-Malonylcarnitine lithium is closely related to some diseases, such as malonic aciduria, non-syndromic cleft lip with or without cleft palate, etc .
Referencia número: HY-147376
No. CAS: 192323-14-1
Target:
Áreas de investigación:
hACC2-IN-1 is a potent acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 value of 2.5 μM (hACC2). hACC2-IN-1 could be used for obesity research .
Referencia número: HY-P3788
No. CAS: 168135-79-3
Referencia número: HY-CE01889
Synonyms: malonyl-coenzyme A methyl ester
Target:
Áreas de investigación:
Malonyl-CoA,methylester (Malonyl-coenzyme A methyl ester) is a coenzyme A derivative .
Referencia número: HY-W015300S
No. CAS: 19031-57-3
Synonyms: Octanedioic acid-d4
Referencia número: HY-W015300S1
No. CAS: 169397-99-3
Synonyms: Octanedioic acid-d12
Referencia número: HY-CE01311
No. CAS: 60051-91-4
Synonyms: D2-malonyl-coenzyme a
Target:
Áreas de investigación:
D2-malonyl-CoA (D2-malonyl-coenzyme A) is a coenzyme A derivative .
Referencia número: HY-B2007R
No. CAS: 79241-46-6
Áreas de investigación:
Fluazifop-P-butyl (Standard) is the analytical standard of Fluazifop-P-butyl (HY-B2007). This product is intended for research and analytical applications. Fluazifop-P-butyl is an orally active herbicide and ACCase inhibitor. Fluazifop-P-butyl blocks the formation of malonyl-CoA, disrupts lipid synthesis in sensitive plants, and exhibits concentration-dependent phytotoxicity to non-target maize seedlings. Fluazifop-P-butyl induces oxidative stress in male Wistar rats, impairs their liver and kidney functions, and disrupts testicular function .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
