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mixed function oxidase

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By Targets:	Xanthine Oxidase (1) BCRP (1) Cholinesterase (ChE) (1) Cytochrome P450 (1) Environmental Pollutants (1) GLUT (1) Glutathione S-transferase (1) Insecticide (1) Oxidative Phosphorylation (3) Parasite (2) Reactive Oxygen Species (ROS) (1) Reference Standards (1)
By Research Areas:	Infection (1) Metabolic Disease (3)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Targets Recommended: Mixed Lineage Kinase Amino Acid Oxidase Lysyl Oxidase Glycolate Oxidase Aldehyde Oxidase (AO) Pyruvate Oxidase Xanthine Oxidase NADPH Oxidase Monoamine Oxidase Protoporphyrinogen IX oxidase VAP-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0055

3-Cyano-7-ethoxycoumarin 1 Publications Verification	Cytochrome P450	Others
3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research .

HY-B0840

Chlorfenapyr	Environmental Pollutants Parasite Oxidative Phosphorylation	Metabolic Disease
Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .

HY-B0840R

Chlorfenapyr (Standard)	Oxidative Phosphorylation Parasite Reference Standards	Metabolic Disease
Chlorfenapyr (Standard) is the analytical standard of Chlorfenapyr. This product is intended for research and analytical applications. Chlorfenapyr is a pyrrole insecticide. Chlorfenapyr has a mode of action: the mixed function oxidase oxidizes and removes the Nethoxymethyl group to form the active metabolite, CL 303268. Chlorfenapyr is used for termite control and crop protection against a variety of insect and mite pests .

HY-182000

Xanthine oxidase-IN-23	Xanthine Oxidase BCRP GLUT	Metabolic Disease
Xanthine oxidase-IN-23 (Compound BPF) is an orally active, reversible, mixed-type Xanthine oxidase inhibitor with an IC₅₀ of 3.33 μM. Xanthine oxidase-IN-23 directly binds to XOD in a reversible mixed-type manner to inhibit its catalytic activity. Xanthine oxidase-IN-23 upregulates ABCG2 and downregulates GLUT9 to promote renal urate excretion. Xanthine oxidase-IN-23 reduces serum urate levels and improves renal function in hyperuricemic mice. Xanthine oxidase-IN-23 can be used in the research of hyperuricemia .

HY-N18024

Kaempferol-3-O-glu-rha-glu	Insecticide Cholinesterase (ChE) Glutathione S-transferase Oxidative Phosphorylation Reactive Oxygen Species (ROS)	Infection
Kaempferol-3-O-glu-rha-glu is an insecticide. Kaempferol-3-O-glu-rha-glu inhibits activities of the enzymes CarE, GSTs, MFO, and AChE. Kaempferol-3-O-glu-rha-glu exhibits cytotoxicity and disrupts mitochondrial membrane potential and increases ROS production. Kaempferol-3-O-glu-rha-glu can be used for the infection .

Cat. No.	Product Name	Type

HY-D0055

3-Cyano-7-ethoxycoumarin 1 Publications Verification	Fluorescent Dyes
3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research .

Kaempferol-3-O-glu-rha-glu	Structural Classification Myrsine stolonifera(Koidz.) E. Walker Phenols Polyphenols Plants Primulaceae Source Classification	Insecticide Cholinesterase (ChE) Glutathione S-transferase Oxidative Phosphorylation Reactive Oxygen Species (ROS)
Kaempferol-3-O-glu-rha-glu is an insecticide. Kaempferol-3-O-glu-rha-glu inhibits activities of the enzymes CarE, GSTs, MFO, and AChE. Kaempferol-3-O-glu-rha-glu exhibits cytotoxicity and disrupts mitochondrial membrane potential and increases ROS production. Kaempferol-3-O-glu-rha-glu can be used for the infection .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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mixed function oxidase

Inhibitors & Agonists

Fluorescent Dyes

NaturalProducts

Natural
Products