117620-77-6
117620-77-6
Chemical Structure
3-Cyano-7-ethoxycoumarin
- CAS No.: 117620-77-6
- Formula:C12H9NO3
- Molecular Weight:215.20
IUPAC Name: 7-ethoxy-2-oxo-2H-chromene-3-carbonitrile
InChIKey: YAFGHMIAFYQSCF-UHFFFAOYSA-N
SMILES: N#CC1=CC2=CC=C(OCC)C=C2OC1=O
Biological Activity: 3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Cyano-7-ethoxycoumarin | 97.40% | 3-Cyano-7-ethoxycoumarin is a fluorescent cytochrome P-450 substrate that generates a blue fluorescent product upon enzymatic cleavage. 3-Cyano-7-ethoxycoumarin is used to detect the activity of mixed-function oxidases in isolated rat hepatocytes. 3-Cyano-7-ethoxycoumarin serves as a biological dye and indicator for research. | ||||||||||||||||||||
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References
- [1]. White IN, et al. A continuous fluorometric assay for cytochrome P-450-dependent mixed function oxidases using 3-cyano-7-ethoxycoumarin. Anal Biochem. 1988;172(2):304-310. [Content Brief]
- [2]. Stresser DM, et al. Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4. Drug Metab Dispos. 2002;30(7):845-852. [Content Brief]
Keywords
