6 Results for "

offset

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "offset" in MCE Product Catalog:

1
1 Cited Publications
Art. -Nr.: HY-155108B
Reinheit:  99.88%
Target:  

Arginase

Forschungsgebiete:  

Cancer

OATD-02 hydrochloride is the hydrochloride salt form of OATD-02 (HY-155108). OATD-02 hydrochloride an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 hydrochloride bolishes tumor immunosuppression induced by both arginases. OATD-02 hydrochloride can be used for melanoma study .
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Art. -Nr.: HY-155108
CAS. Nr.: 2146132-73-0
Target:  

Arginase

Forschungsgebiete:  

Cancer

OATD-02 is an orally active, competitive, reversible, noncovalent dual inhibitor of Arginase1 and 2. OATD-02 is a slow offset inhibitor, blocking intracellular arginases with IC50s of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1), respectively. OATD-02 abolishes tumor immunosuppression induced by both arginases. OATD-02 can be used for melanoma study .
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Art. -Nr.: HY-32927
CAS. Nr.: 150255-96-2
Forschungsgebiete:  

Others

3-Cyanophenylboronic acid is an arylboronic acid-based boronic acid reagent that serves as a coupling partner in Suzuki-Miyaura cross-coupling reactions. 3-Cyanophenylboronic acid participates in reactions to synthesize 4'-propoxybiphenyl-3-carbonitrile .
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Art. -Nr.: HY-167885
CAS. Nr.: 1450615-41-4
Target:  

iGluR

SN-35210 free base, an ester analogue, is designed for rapid offset via esterase-mediated hydrolysis .
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Art. -Nr.: HY-N14785
CAS. Nr.: 79495-61-7
Deflectin 1a is an antibiotic with the activity of lysing bacteria, lysing red blood cells and inhibiting Ehrlich ascites cancer cells, and its activity can be offset by adding serum or serum albumin .
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Art. -Nr.: HY-165443
CAS. Nr.: 468-76-8
Synonyms: Nervocidine
Cassaine (Nervocidine) is a Na +/K +-ATPase inhibitor. Cassaine stabilizes phosphorylated intermediates, slows spontaneous dephosphorylation and blocks potassium-stimulated dephosphorylation. Cassaine exhibits non-competitive inhibition with respect to K +, shows inhibition enhanced by Pi and antagonized by Na +. Cassaine induces positive inotropic effects in perfused hearts with faster inotropy offset. Cassaine can be used for research on cardiac arrhythmias .
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