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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
31 Results for "
oligoribonucleotide
" in MedChemExpress (MCE) Product Catalog:
Products (31)
31 Results for "oligoribonucleotide" in MCE Product Catalog:
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Olaptesed pegol (NOX-A12) is a L-oligoribonucleotide aptamer targeting CXCL12 based on a pegylated structure. Olaptesed pegol neutralizes CXCL12, and CXCL12 inhibition mobilizes chronic lymphocytic leukemia cells into the circulation and prevents their homing into the protective microenvironment. Olaptesed pegol can enhances the infiltration of human primary T cells and NK cells and inhibit tumor growth companied with anti-PD-1 antibody. Olaptesed pegol can be used for researches of colon cancer and lymphocytic leukemia .
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Olaptesed pegol (NOX-A12) sodium is a L-oligoribonucleotide aptamer targeting CXCL12 based on a pegylated structure. Olaptesed pegol sodium neutralizes CXCL12, and CXCL12 inhibition mobilizes chronic lymphocytic leukemia cells into the circulation and prevents their homing into the protective microenvironment. Olaptesed pegol sodium can enhances the infiltration of human primary T cells and NK cells and inhibit tumor growth companied with anti-PD-1 antibody. Olaptesed pegol sodium can be used for researches of colon cancer and lymphocytic leukemia .
Cat. No.: HY-43057
CAS No.: 64350-24-9
Synonyms: N-Isobutyrylguanosine
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iBu-rG (N-Isobutyrylguanosine) is a nucleoside compound that can be used to synthesize oligoribonucleotides .
Cat. No.: HY-W089288
CAS No.: 136834-20-3
Synonyms: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine
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2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
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2'-F-Bz-dC Phosphoramidite can be used in the synthesis of oligoribonucleotide (such as DNA and RNA). 2'-F-Bz-dC Phosphoramidite also used for synthesis antiviral agent to inhibit the replication of virus. 2'-F-Bz-dC Phosphoramidite contains a phosphorothioate backbone, to synthesise antisense oligonucleotide analogs to induce apoptosis in cancer cells .
Cat. No.: HY-164247A
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UnyLinker 12 TEA is a universal linker that can be used for the synthesis of oligoribonucleotides .
Cat. No.: HY-W131753
CAS No.: 159414-97-8
Synonyms: N-Acetyl-2′-deoxy-2′-fluorocytidine
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2'-F-Ac-C (N-Acetyl-2′-deoxy-2′-fluorocytidine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
Cat. No.: HY-164247
CAS No.: 852684-08-3
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UnyLinker 12 is a universal linker that can be used for the synthesis of oligoribonucleotides .
Cat. No.: HY-W016011
CAS No.: 68892-42-2
Synonyms: N2-Isobutyryl-2'-deoxyguanosine
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iBu-dG (N2-Isobutyryl-2'-deoxyguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
Cat. No.: HY-160227A
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ORN 06 (sodium) s a synthetic single-stranded U-rich RNA and contains 6 repeats of the UUGU sequence motif. The GU-rich oligoribonucleotides (ORNs) are able to stimulate TLR7 .
Cat. No.: HY-W008388
CAS No.: 4546-55-8
Synonyms: N6-Benzoyladenosine
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Bz-rA (N6-Benzoyladenosine) is a nucleoside derivative with an N6 protecting group. Bz-rA is mainly used as a synthetic intermediate to participate in photocatalytic oxidative cyclization reactions and synthesize oligoribonucleotides. Bz-rA can be used to efficiently construct heterocyclic skeletons in photochemical conversions and protect the ribose moiety to regulate the cyclization pathway .
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5'-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides .
Cat. No.: HY-21286
CAS No.: 63264-29-9
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N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate (e.g., used in antisense oligonucleotides, mRNA modification), for example, it is a key monomer for the synthesis of 2'-O-methyl oligoribonucleotides. N2-Isobutyryl-2'-O-methylguanosine enables the final product to form stable double strands with complementary RNA and is not easily degraded by nucleases. N2-Isobutyryl-2'-O-methylguanosine is mainly used in molecular biology research, and can be used to prepare RNA hybridization probes or participate in related biochemical research such as pre-mRNA splicing mechanisms .
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5'-O-DMT-Ri can be used in the synthesis of oligoribonucleotides .
Cat. No.: HY-W011125
CAS No.: 4546-72-9
Synonyms: N6-Benzoyl-2'-deoxyadenosine
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Bz-dA (N6-Benzoyl-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides
Cat. No.: HY-178674A
CAS No.: 240137-51-3
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Im-m7GDP sodium is a capping reagent and also the P-imidazolide of N7-methylguanosine 5'-diphosphate. Im-m7GDP sodium introduces an m7G cap structure to the monophosphate group of branched oligoribonucleotides, and is used in nucleic acid synthesis-related research .
Cat. No.: HY-177641
CAS No.: 1390631-57-8
Synonyms: NOX-H94
Lexaptepid Pegol is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
Cat. No.: HY-177641A
Synonyms: NOX-H94 sodium
Lexaptepid Pegol sodium is a pegylated structured L-oligoribonucleotide. It binds and inhibits hepcidin.
Cat. No.: HY-W113972
CAS No.: 80681-25-0
Synonyms: 2′-Deoxy-2′-fluoro-N-isobutyrylguanosine
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2'-F-iBu-G (2′-Deoxy-2′-fluoro-N-isobutyrylguanosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides .
Cat. No.: HY-W114328
CAS No.: 199593-08-3
Synonyms: N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine
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DMT-OMe-rC(Ac) (N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methylcytidine) is a nucleotide derivative that can be used to synthesize oligoribonucleotides .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
