UnyLinker 12 TEA

Cat. No.: HY-164247A Purity: 99.97%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

UnyLinker 12 TEA is a universal linker that can be used for the synthesis of oligoribonucleotides.

For research use only. We do not sell to patients.

UnyLinker 12 TEA Chemical Structure

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	Get quote

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Other Forms of UnyLinker 12 TEA:

UnyLinker 12 Get quote

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Biological Activity
Purity & Documentation
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Description

UnyLinker 12 TEA is a universal linker that can be used for the synthesis of oligoribonucleotides^[1].

In Vitro

UnyLinker 12 TEA is a universal linker that can be used for the synthesis of oligoribonucleotides^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

697.94

Formula

C₃₉H₃₅NO₁₀.1/5C₆H₁₅N

Appearance

Solid

Color

White to off-white

SMILES

OC(CCC(O[C@H]1[C@](O2)([H])[C@](C(N(C3=CC=CC=C3)C4=O)=O)([H])[C@]4([H])[C@]2([H])[C@H]1OC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC)=O)=O.CCN(CC)CC.[1/5]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (143.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.4328 mL	7.1639 mL	14.3279 mL
5 mM	0.2866 mL	1.4328 mL	2.8656 mL
10 mM	0.1433 mL	0.7164 mL	1.4328 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.97%

Select Batch:

Data Sheet (272 KB) SDS (394 KB)

COA (251 KB) HNMR (294 KB) LCMS (100 KB)

Handling Instructions (2659 KB)

References

[1]. Vasulinga T. Ravikumar, et al. UnyLinker: An Efficient and Scaleable Synthesis of Oligonucleotides Utilizing a Universal Linker Molecule: A Novel Approach To Enhance the Purity of Drugs. Org. Process Res. Dev. 2008, 12, 3, 399-410.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.4328 mL	7.1639 mL	14.3279 mL	35.8197 mL
	5 mM	0.2866 mL	1.4328 mL	2.8656 mL	7.1639 mL
	10 mM	0.1433 mL	0.7164 mL	1.4328 mL	3.5820 mL
	15 mM	0.0955 mL	0.4776 mL	0.9552 mL	2.3880 mL
	20 mM	0.0716 mL	0.3582 mL	0.7164 mL	1.7910 mL
	25 mM	0.0573 mL	0.2866 mL	0.5731 mL	1.4328 mL
	30 mM	0.0478 mL	0.2388 mL	0.4776 mL	1.1940 mL
	40 mM	0.0358 mL	0.1791 mL	0.3582 mL	0.8955 mL
	50 mM	0.0287 mL	0.1433 mL	0.2866 mL	0.7164 mL
	60 mM	0.0239 mL	0.1194 mL	0.2388 mL	0.5970 mL
	80 mM	0.0179 mL	0.0895 mL	0.1791 mL	0.4477 mL
	100 mM	0.0143 mL	0.0716 mL	0.1433 mL	0.3582 mL

UnyLinker 12 TEA Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UnyLinker 12UnyLinker12UnyLinker-12Nucleoside Antimetabolite/AnaloglinkeroligoribonucleotidesInhibitorinhibitorinhibit

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