5'-O-DMT-PAC-dA
Based on 1 Customer Validation
5'-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides.
For research use only. We do not sell to patients.
- Purity: 99.62%
- CAS No.: 110522-82-2
- Formula: C39H37N5O7
- Molecular Weight:687.74
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All DNA/RNA Synthesis Isoforms
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Biological Activity
Chemical Information
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CAS No. 110522-82-2
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Appearance Solid
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Molecular Weight 687.74
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Formula C39H37N5O7
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Color White to off-white
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SMILES
O[C@H]1C[C@H](N(C=N2)C3=C2C(NC(COC4=CC=CC=C4)=O)=NC=N3)O[C@@H]1COC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 250 mg/mL (363.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4540 mL | 7.2702 mL | 14.5404 mL | 36.3509 mL |
| 5 mM | 0.2908 mL | 1.4540 mL | 2.9081 mL | 7.2702 mL | |
| 10 mM | 0.1454 mL | 0.7270 mL | 1.4540 mL | 3.6351 mL | |
| 15 mM | 0.0969 mL | 0.4847 mL | 0.9694 mL | 2.4234 mL | |
| 20 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8175 mL | |
| 25 mM | 0.0582 mL | 0.2908 mL | 0.5816 mL | 1.4540 mL | |
| 30 mM | 0.0485 mL | 0.2423 mL | 0.4847 mL | 1.2117 mL | |
| 40 mM | 0.0364 mL | 0.1818 mL | 0.3635 mL | 0.9088 mL | |
| 50 mM | 0.0291 mL | 0.1454 mL | 0.2908 mL | 0.7270 mL | |
| 60 mM | 0.0242 mL | 0.1212 mL | 0.2423 mL | 0.6058 mL | |
| 80 mM | 0.0182 mL | 0.0909 mL | 0.1818 mL | 0.4544 mL | |
| 100 mM | 0.0145 mL | 0.0727 mL | 0.1454 mL | 0.3635 mL |