2'-F-Bz-A
Based on 1 Customer Validation
2'-F-Bz-A (N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine) is a nucleoside analog that can be used to synthesize oligoribonucleotides.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 136834-20-3
- Formula: C17H16FN5O4
- Molecular Weight:373.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Oligonucleotides are a class of short-chain nucleic acids composed of deoxyribonucleotides or ribonucleotides; by pairing with DNA, mRNA, or pre-mRNA based on the principle of complementary base pairing, they can precisely "silence" specific genes, thereby preventing the expression of numerous proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136834-20-3
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Appearance Solid
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Molecular Weight 373.34
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Formula C17H16FN5O4
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Color White to off-white
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SMILES
O=C(C1=CC=CC=C1)NC2=C3N=CN([C@H]4[C@H](F)[C@H](O)[C@@H](CO)O4)C3=NC=N2
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Synonyms
N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (267.85 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6785 mL | 13.3926 mL | 26.7852 mL | 66.9631 mL |
| 5 mM | 0.5357 mL | 2.6785 mL | 5.3570 mL | 13.3926 mL | |
| 10 mM | 0.2679 mL | 1.3393 mL | 2.6785 mL | 6.6963 mL | |
| 15 mM | 0.1786 mL | 0.8928 mL | 1.7857 mL | 4.4642 mL | |
| 20 mM | 0.1339 mL | 0.6696 mL | 1.3393 mL | 3.3482 mL | |
| 25 mM | 0.1071 mL | 0.5357 mL | 1.0714 mL | 2.6785 mL | |
| 30 mM | 0.0893 mL | 0.4464 mL | 0.8928 mL | 2.2321 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6696 mL | 1.6741 mL | |
| 50 mM | 0.0536 mL | 0.2679 mL | 0.5357 mL | 1.3393 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4464 mL | 1.1161 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8370 mL | |
| 100 mM | 0.0268 mL | 0.1339 mL | 0.2679 mL | 0.6696 mL |