44 Results for "

posttranslational modifications

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "posttranslational modifications" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-145651
CAS No.: 2166487-23-4
Purity:  99.89%
Synonyms: NRD167
Target:  

Sirtuin

Research Areas:  

Cancer

Et-29 is a potent and selective SIRT5 inhibitor (Ki=40 nM) .
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Cat. No.: HY-126370A
CAS No.: 313263-08-0
Purity:  ≥95.0%
Geranylgeranyl pyrophosphate triammonium is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate triammonium is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate triammonium regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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Cat. No.: HY-W116606
CAS No.: 1357078-03-5
Target:  

Fluorescent Dye

Research Areas:  

Others

Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification .
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Cat. No.: HY-126370
CAS No.: 6699-20-3
Geranylgeranyl pyrophosphate is a type of isoprenoid metabolic intermediate, mainly synthesized through the mevalonate pathway. Geranylgeranyl pyrophosphate is a key precursor in various biological synthesis processes, especially as a necessary substrate for post-translational modification of proteins - geranylgeranyl phosphorylation. Geranylgeranyl pyrophosphate regulates various cellular processes and disease progression through protein geranylgeranyl phosphorylation, such as activating the YAP signaling pathway, promoting cell proliferation and inhibiting apoptosis; promoting IL-2 production and STAT5 phosphorylation; and influencing metabolic homeostasis and cancer, etc .
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Cat. No.: HY-137042
CAS No.: 1223357-57-0
Purity:  98.15%
Synonyms: Alkyne-Cy5
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-136276
CAS No.: 780009-55-4
Purity:  99.48%
Research Areas:  

Others

DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation .
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Cat. No.: HY-W414799
CAS No.: 79416-87-8
Nε,Nε-Dimethyl-L-lysine monohydrochloride is an unnatural amino acid with the activity of regulating protein post-translational modification. Nε,Nε-Dimethyl-L-lysine monohydrochloride can be used as a tool for epigenetic research to promote the research process of acetylation and methylation. Nε,Nε-Dimethyl-L-lysine monohydrochloride is also widely used in compound development and biochemical research.
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Cat. No.: HY-19804
CAS No.: 1863117-91-2
Synonyms: Photo lysine
Photo-lysine, a new lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications.
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Cat. No.: HY-126171
CAS No.: 34994-11-1
Target:  

Endogenous Metabolite

Research Areas:  

Others

Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH) .
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Cat. No.: HY-P2255
Target:  

Histone Demethylase

Research Areas:  

Others

H3K4(Me) (1-20), a histone peptide. H3K4me is an intricately regulated posttranslational modification, which is broadly associated with enhancers and promoters of actively transcribed genomic loci .
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Cat. No.: HY-19804A
Photo-lysine hydrochloride, a new lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications.
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Cat. No.: HY-P10111A
Synonyms: H3(1-15)K9me3 TFA
Research Areas:  

Others

Histone H3K9me3 (1-15) (H3(1-15)K9me3) TFA is used as substrate. Histone H3K9me3 is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin .
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Cat. No.: HY-P10111
CAS No.: 951011-30-6
Synonyms: H3(1-15)K9me3
Target:  

Peptides

Research Areas:  

Inflammation/Immunology Cancer

Histone H3K9me3 (1-15) (H3(1-15)K9me3) is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin. Trimethylation of histone H3 at lysine 9 is associated with gene repression, prevents transcription factor binding .
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Cat. No.: HY-114005
CAS No.: 607368-97-8
Target:  

CMV

Research Areas:  

Infection

SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications .
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Cat. No.: HY-D2283
Photo-DL-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
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Cat. No.: HY-121722
CAS No.: 82543-85-9
Research Areas:  

Cancer

Deoxyhypusine is an unusual amino acid formed during the posttranslational modification of eukaryotic translation initiation factor 5A (eIF-5A) by the enzyme deoxyhypusine hydroxylase (DOHH) .
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Cat. No.: HY-157140
CAS No.: 1644442-22-7
Research Areas:  

Others

HibK is is a new type of histone mark that is widely distributed in histone proteins. HibK as a useful tool can be used for probing post-translational modification by site-specifically incorporate HibK into proteins .
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Cat. No.: HY-D2283S1
Photo-lysine-d2 is the deuterium labeled Photo-lysine. Photo-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
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Cat. No.: HY-D2283S2
Photo-lysine-d2-1 is the deuterium labeled Photo-lysine. Photo-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
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Cat. No.: HY-D2283S
Photo-DL-lysine-d2 is the deuterium labeled Photo-DL-lysine (HY-D2283). Photo-DL-lysine is a DL-lysine-based photo-reactive amino acid, captures proteins that bind lysine post-translational modifications .
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