Histone H3K9me3 (1-15)
Histone H3K9me3 (1-15) (H3(1-15)K9me3) is a histone posttranslational modification (PTM) that has emerged as hallmark of pericentromeric heterochromatin. Trimethylation of histone H3 at lysine 9 is associated with gene repression, prevents transcription factor binding.
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- CAS No.: 951011-30-6
- Formula: C66H124N25O21+
- Molecular Weight:1603.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 951011-30-6
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Molecular Weight 1603.85
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Formula C66H124N25O21+
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Synonyms
H3(1-15)K9me3
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Sequence
Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-{Lys(Me3)}-Ser-Thr-Gly-Gly-Lys-Ala
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Sequence Shortening
ARTKQTAR-{Lys(Me3)}-STGGKA
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Woon EC, et al. Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. Angew Chem Int Ed Engl. 2012 Feb 13;51(7):1631-4. [Content Brief]
[2]. Mosch K, et al. HP1 recruits activity-dependent neuroprotective protein to H3K9me3 marked pericentromeric heterochromatin for silencing of major satellite repeats. PLoS One. 2011 Jan 18;6(1):e15894. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Histone H3K9me3 (1-15) Related Classifications
HY-P10111 Related Classifications
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