1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Cyanine5 alkyne

Cyanine5 alkyne (Synonyms: Alkyne-Cy5)

Cat. No.: HY-137042
Handling Instructions

Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC).

For research use only. We do not sell to patients.

Cyanine5 alkyne Chemical Structure

Cyanine5 alkyne Chemical Structure

CAS No. : 1223357-57-0

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Description

Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC)[1][2].

In Vitro

Cyanine5 alkyne (Alkyne-Cy5) (1-1000 nM) significantly inhibits 3D mammosphere formation in MCF7 cells between 500 nM and 1000 nM and can act as a mitochondrial oxidative phosphorylation (OXPHOS) inhibitor, inducing glycolysis to compensate for mitochondrial ATP depletion[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

556.18

Formula

C35H42ClN3O

CAS No.
SMILES

C#CCNC(CCCCC[N+]1=C(/C=C/C=C/C=C2N(C)C3=C(C=CC=C3)C\2(C)C)C(C)(C)C4=C1C=CC=C4)=O.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Cyanine5 alkyne
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