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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
39 Results for "
quinoline derivative
" in MedChemExpress (MCE) Product Catalog:
Products (39)
39 Results for "quinoline derivative" in MCE Product Catalog:
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Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis .
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BCH001, a quinoline derivative, is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in dyskeratosis congenita (DC) induced pluripotent stem cells. BCH001 shows no inhibition of poly(A)-specific ribonuclease (PARN) or several other canonical and non-canonical polynucleotide polymerases. BCH001 is used to regulate aging .
Cat. No.: HY-W015503
CAS No.: 1198-37-4
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4-Methylquinaldine is a quinoline derivative and can be used as a drug intermediate.
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3-Aminopropan-1-ol is both a primary amine and a primary alcohol, and it is widely used as a versatile chemical building block and molecular linker .
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Cat. No.: HY-W008168
CAS No.: 5470-96-2
Synonyms: 2-quinolinecarboxaldehyde
Cat. No.: HY-W004769
CAS No.: 230-27-3
Synonyms: α-Naphthoquinoline
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Benzo[h]quinolone is a widespread environmental pollutant. Benzo[h]quinolone is mutagenic. Benzo(h)quinoline derivatives can serve as G-quadruplex binding agents .
Category:
Alkaloids Neurological Disease Quinoline Alkaloids Endogenous metabolite Disease Research Fields Cancer
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Cat. No.: HY-W012637
CAS No.: 99-03-6
Synonyms: 3'-Aminoacetophenone
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MPT0B392, an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation, leading to apoptosis. MPT0B392 inhibits tubulin polymerization and triggers induction of the mitotic arrest, followed by mitochondrial membrane potential loss and caspases cleavage by activation of JNK and ultimately leads to apoptosis. MPT0B392 is demonstrated to be a novel microtubule-depolymerizing agent and enhances the cytotoxicity of sirolimus in sirolimus-resistant acute leukemic cells and the multidrug resistant cell line .
Cat. No.: HY-172228
CAS No.: 146535-06-0
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RPR-101511 is a 3-substituted quinoline derivative. RPR-101511 is a PDGF receptor tyrosine kinase inhibitor (IC50: 0.001-0.02 μM) .
Synonyms: Cinchoninic acid (Standard); 4-Carboxyquinoline (Standard); NSC 13138 (Standard)
Cat. No.: HY-W016840
CAS No.: 14510-06-6
Cat. No.: HY-186054
CAS No.: 1258387-40-4
Antimalarial agent 57 (308470) is a quinoline methanol derivative with antimalarial activity. Antimalarial agent 57 can be used in malaria research .
Nopol is a quinoline derivative based on nopol that has inhibitory activity against the asexual blood stage of Plasmodium falciparum. Derivatives with different structures have different activities against different Plasmodium strains, and some derivatives have submicromolar EC50 values in specific strains.
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Antibacterial agent 131 is a quinoline derivative. Antibacterial agent 131 has antimicrobial effect. Antibacterial agent 131 destroys the integrity of the fungal cells via blocking ergosterol production .
Cat. No.: HY-164298
CAS No.: 2765728-26-3
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MRGPRX2 modulator-3 (Compound 4-400) is a quinoline derivative and a MRGPRX2 modulator. MRGPRX2 modulator-3 can be used in the research of MRGPRX2-related diseases, such as allergies, pruritus, pain, inflammation and autoimmune diseases, etc .
Cat. No.: HY-156090
CAS No.: 3074451-41-2
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PK-10 is a synergistic antibacterial agent of Fluconazole (HY-B0101) and has strong antifungal activity against a variety of Fluconazole-resistant Candida albicans strains. PK-10 combined with Fluconazole can inhibit hyphae formation and induce the accumulation of reactive oxygen species. It further causes damage to mitochondrial membrane potential, reduces intracellular ATP content, and leads to mitochondrial dysfunction .
Cat. No.: HY-146303
CAS No.: 2770957-08-7
C-RAF kinase-IN-1 (compound 1l) is a potent inhibitor of C-RAF kinase with an IC50 of 0.193 μM. C-RAF kinase-IN-1 is a quinoline derivative. C-RAF kinase-IN-1 has the potential for the research of cancer diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
