611-36-9
611-36-9
Chemical Structure
4-Quinolinol
Synonym(s): Kynurine
- CAS No.: 611-36-9
- Formula:C9H7NO
- Molecular Weight:145.16
IUPAC Name: quinolin-4-ol
InChIKey: PMZDQRJGMBOQBF-UHFFFAOYSA-N
SMILES: OC1=CC=NC2=CC=CC=C12
Biological Activity: 4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune[1][2].
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4-Quinolinol | 99.93% | 4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune. | ||||||||||||||||||||
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4-Quinolinol (Standard) | ≥98% | 4-Quinolinol (Standard) is the analytical standard of 4-Quinolinol. This product is intended for research and analytical applications. 4-Quinolone (Kynurine) is a quinoline derivative. Kynurine pathway modulates tryptophan metabolism and involves in neuroprotective effect. Kynurine promotes tumor cell survival and motility by suppressing antitumor immune. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-321005-Hydroxyquinoline -
Similarity Score 0.92
HY-B1005R8-Hydroxyquinoline (Standard) -
Similarity Score 0.89
HY-W0047215-Hydroxyisoquinoline -
Similarity Score 0.88
HY-W0076034-Chloroquinoline -
Similarity Score 0.88
HY-W001604Quinolin-5-amine -
Similarity Score 0.88
HY-W0025595-Bromoquinoline -
Similarity Score 0.86
HY-W1030784,6-Dihydroxyquinoline -
Similarity Score 0.85
HY-W016535R7-Chloroquinolin-4-ol (Standard) -
Similarity Score 0.85
HY-W018397Tiliquinol -
Explore the MedChemAI to find more analogs
References
- [1]. Pellicciari R, et al. Modulation of the kynurine pathway of tryptophan metabolism in search for neuroprotective agents. Focus on kynurenine-3-hydroxylase. Adv Exp Med Biol. 2003;527:621-8. [Content Brief]
- [2]. Marija Pinne, et al. Cytochrome P450 Gene Regulation: Reporter Assays to Assess Aryl Hydrocarbon Receptor (HLHE76, AhR) Activation and Antagonism. Cytochrome P450. pp 157-174.
