3026790-18-8
3026790-18-8
Chemical Structure
Antibacterial agent 131
- CAS No.: 3026790-18-8
- Formula:C24H17ClN4OS
- Molecular Weight:444.94
IUPAC Name: (E)-2-(2-((2-chloro-6-methoxyquinolin-3-yl)methylene)hydrazinyl)-4-(3-fluorophenyl)thiazole
InChIKey: IKGWZVPDDWNKMS-LGJNPRDNSA-N
SMILES: COC1=CC=C2N=C(C(/C=N/NC3=NC(C4=C5C=CC=CC5=CC=C4)=CS3)=CC2=C1)Cl
Biological Activity: Antibacterial agent 131 is a quinoline derivative. Antibacterial agent 131 has antimicrobial effect. Antibacterial agent 131 destroys the integrity of the fungal cells via blocking ergosterol production[1].
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Antibacterial agent 131 | 98.52% | Antibacterial agent 131 is a quinoline derivative. Antibacterial agent 131 has antimicrobial effect. Antibacterial agent 131 destroys the integrity of the fungal cells via blocking ergosterol production. | ||||||||||||||||||||
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Antibacterial agent 132 | Antibacterial agent 132 has anticandidal effects against C. parapsilosis (ATCC 22019) and C. krusei (ATCC 6258) with MIC90 values of <0.06 μg/mL and 62.50 μg/mL, respectively. Antibacterial agent 132 inhibits aromatase enzyme with an IC50 of 0.047μM. | |||||||||||||||||||||
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