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Results for "

rabbit lung ACE

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

2

Peptides

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-23093
    L-Aspartyl-L-phenylalanine

    		Angiotensin-converting Enzyme (ACE) Drug Metabolite Cardiovascular Disease
    L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
    L-Aspartyl-L-phenylalanine
  • HY-P3991
    Bradykinin potentiator C

    		Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Bradykinin potentiator C is a potent angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 7.1 μM for rabbit lung ACE. Bradykinin potentiator C is a postulated prototype of functional peptide .
    Bradykinin potentiator C
  • HY-P2605
    Tuna AI

    		Angiotensin-converting Enzyme (ACE) Metabolic Disease
    Tuna AI, an angiotensin-converting enzyme (ACE) inhibitor, exhibits IC50 values of 1 μM and 2 μM for ACEs from bovine and rabbit lungs, respectively .
    Tuna AI
  • HY-131280R
    Devaleryl Valsartan Impurity (Standard)

    		Drug Metabolite Reference Standards Others
    L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
    Devaleryl Valsartan Impurity (Standard)
  • HY-23093R
    L-Aspartyl-L-phenylalanine (Standard)

    		Reference Standards Angiotensin-converting Enzyme (ACE) Drug Metabolite Cardiovascular Disease
    L-Aspartyl-L-phenylalanine (Standard) is the analytical standard of L-Aspartyl-L-phenylalanine. This product is intended for research and analytical applications. L-Aspartyl-L-phenylalanine is a metabolite of aspartame that can inhibit angiotensin converting enzyme (ACE) purified from rabbit lungs with a Ki of 11 μM .
    L-Aspartyl-L-phenylalanine (Standard)
  • HY-105572
    Moveltipril calcium

    MC-838 calcium

    		 Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin .
    Moveltipril calcium
  • HY-182407
    CV 5975

    		Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    CV 5975 is an orally active angiotensin converting enzyme (ACE) competitive inhibitor with a rabbit lung ACE IC50 of 3.1 nM and Ki values of 2.6 nM. CV 5975 inhibits ACE in plasma, aorta, kidney, and brain, intensifying inhibition with repeated administration. CV 5975 inhibits Angiotensin I (HY-P1032)-induced pressor responses and ileum contraction, and augments bradykinin-induced ileum contraction and depressor responses. CV 5975 reduces blood pressure via ACE-independent mechanisms, with sustained action across multiple hypertensive and normotensive animal models, intensified by repeated dosing or Hydrochlorothiazide (HY-B0252) co-administration. CV 5975 can be used for the research of hypertension .
    CV 5975
  • HY-182445
    FPL 66564

    		Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    FPL 66564 is a short-acting angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5.7 nM against rabbit ACE. FPL 66564 inhibits ACE activity at the functional level and is hydrolyzed in human blood into inactive hydrophilic metabolites. FPL 66564 modulates angiotensin I-induced pressor responses in anesthetized rats, and its effects rapidly return to baseline after cessation of intravenous infusion. FPL 66564 can be used for research on cardiovascular regulation related to critical illness .
    FPL 66564
  • HY-N19889
    Plantainoside E

    		Others Cardiovascular Disease
    Plantainoside E is a phenylpropanoid glycoside. Plantainoside E can be isolated from the leaves of Plantago major L. Plantainoside E shows no angiotensin-converting enzyme inhibitory activity. Plantainoside E can be used in hypertension research .
    Plantainoside E
  • HY-182301
    CP 71362

    		Renin Cardiovascular Disease
    CP 71362 is a renin inhibitor, a highly potent substrate-analog transition state mimic with antihypertensive properties. CP 71362 exhibits significant inhibitory activity against plasma renin from rats, dogs, and humans (IC50 values are 3 nM, 0.0033 nM, and 20 nM, respectively). CP 71362 reduces the mean arterial pressure of anesthetized and conscious sodium-depleted animals in a dose-dependent manner, and has pharmacokinetic characteristics of rapid elimination and short duration of action. CP 71362 can be used in research related to hypertension and congestive heart failure .
    CP 71362

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