180341-69-9
180341-69-9
Chemical Structure
Acein-1
- CAS No.: 180341-69-9
- Formula:C44H66N10O12
- Molecular Weight:927.05
InChIKey: VSNQHTMELQVEOS-LHGQKOGQSA-N
SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(C)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O
Biological Activity: Acein-1 is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 16 μM against rabbit lung ACE. Acein-1 does not bind to the catalytic site of ACE and cannot be hydrolyzed by ACE. Acein-1 can be used in the research of hypertension[1].
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Acein-1 | Acein-1 is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 16 μM against rabbit lung ACE. Acein-1 does not bind to the catalytic site of ACE and cannot be hydrolyzed by ACE. Acein-1 can be used in the research of hypertension. | |||||||||||||||||||||
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YLYEIA-(Arg-13C6,15N4) TFA | YLYEIA-(Arg-13C6,15N4) TFA is the 13C- and 15N-labeled YLYEIA. | |||||||||||||||||||||
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References
Keywords
