Plantainoside E
Plantainoside E is a phenylpropanoid glycoside. Plantainoside E can be isolated from the leaves of Plantago major L. Plantainoside E shows no angiotensin-converting enzyme inhibitory activity. Plantainoside E can be used in hypertension research.
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- CAS No.: 136083-88-0
- Formule: C31H40O16
- Masse moléculaire:668.64
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Plantainoside E (100 µM; 10 min-1 h) shows no angiotensin I-converting enzyme inhibitory activity against rabbit lung ACE at a concentration of 100 µM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 136083-88-0
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Masse moléculaire 668.64
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Formule C31H40O16
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SMILES
O[C@@H]([C@@H](O[C@@H]([C@H]1O)COC(/C=C/C2=CC(OC)=C(C=C2)O)=O)OCCC3=CC(O)=C(C=C3)OC)[C@H]1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Research Protocol for Cardiovascular Diseases
Cardiovascular disease can be modeled as maladaptive cardiac remodeling, where ischemic injury or pressure overload activates inflammatory signaling, fibroblast activation, extracellular-matrix deposition, cardiomyocyte hypertrophy, vascular remodeling, and progressive ventricular dysfunction. The TGF-β/SMAD axis is a central profibrotic pathway after myocardial injury and pressure overload, while innate immune and cytokine pathways regulate leukocyte recruitment, scar formation, and adverse remodeling. Key unresolved questions include which inflammatory signals are reparative versus harmful, when fibrosis is protective versus maladaptive, and whether pathway inhibition improves function without weakening necessary infarct healing or compensatory remodeling.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)