12 Results for "

rhubarb

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "rhubarb" in MCE Product Catalog:

18
18 Publications Verification
Cat. No.: HY-N0105
CAS No.: 478-43-3
Synonyms: Rheic Acid; rhubarb yellow; Monorhein
Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects [1] .
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10
10 Cited Publications
Cat. No.: HY-N0108
CAS No.: 521-61-9
Synonyms: Parietin; Rheochrysidin
Physcion (Parietin), an anthraquinone derivative derived from the traditional Chinese medicine rhubarb, is an effective oral active 6-phosphogluconate dehydrogenase inhibitor with blood-brain barrier permeability, with IC50 and Kd values of 38.5 μM and 26.0 μM, respectively. Additionally, Physcion is an inhibitor of the <>bTLR4/NF-κB signaling pathway, exhibiting anti-inflammatory, antibacterial, and anticancer effects, and can induce Apoptosis and Autophagy in cancer cells .
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2
2 Cited Publications
Cat. No.: HY-N2237
CAS No.: 94356-26-0
Synonyms: Quzhaqigan
Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 μM and 11.06 μM against arginase I and arginase II, respectively.
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1
1 Cited Publications
Cat. No.: HY-N6082
CAS No.: 34298-86-7
Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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Cat. No.: HY-N0105R
CAS No.: 478-43-3
Synonyms: Rheic Acid (Standard); rhubarb yellow (Standard); Monorhein (Standard)
Rhein (Standard) is the analytical standard of Rhein. This product is intended for research and analytical applications.
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Cat. No.: HY-N10371
CAS No.: 84268-38-2
Physcion-8-O-β-gentiobioside is an anthraquinone glycoside isolated from rhubarb roots .
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Cat. No.: HY-N10322
CAS No.: 641-90-7
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system .
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Cat. No.: HY-N9777
CAS No.: 106533-60-2
Procyanidin B-5 3,3'-di-O-gallate is a potent inhibitor of squalene epoxidase with an IC50 of 0.55 μM. Procyanidin B-5 3,3'-di-O-gallate reduces cholesterol by inhibiting squalene epoxidase activity .
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Cat. No.: HY-N2237R
CAS No.: 94356-26-0
Synonyms: Quzhaqigan (Standard)
Piceatannol 3'-O-glucoside (Standard) is the analytical standard of Piceatannol 3'-O-glucoside. This product is intended for research and analytical applications. Piceatannol 3'-O-glucoside, an active component of Rhubarb, activates endothelial nitric oxide (NO) synthase through inhibition of arginase activity with IC50s of 11.22 μM and 11.06 μM against arginase I and arginase II, respectively.
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Cat. No.: HY-N6082R
CAS No.: 34298-86-7
Rhein 8-O-β-D-Glucopyranoside (Standard) is the analytical standard of Rhein 8-O-β-D-Glucopyranoside (HY-N6083). This product is intended for research and analytical applications. Rhein 8-O-β-D-Glucopyranoside is an orally active glycoside found in Rhubarb. Rhein 8-O-β-D-Glucopyranoside attenuates high glucose-induced apoptosis, recovers altered lincRNA ANRIL and let-7a expression, reverses high glucose-altered Bcl-2 and cleaved caspase-3 protein expression, and inhibits TGF-β1/Smad signaling. Rhein 8-O-β-D-Glucopyranoside accelerates Sennoside A (HY-N0365) metabolism, stimulates sennoside A purgative activity. Rhein 8-O-β-D-Glucopyranoside inhibits bacterial biofilm formation, suppresses its virulence gene expression, and exerts antibacterial activity. Rhein 8-O-β-D-Glucopyranoside can be used for the research of diabetic nephropathy, constipation, and infection .
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Cat. No.: HY-W686479
CAS No.: 5302-46-5
Research Areas:  

Others

N-Oxalyl-L-alanine is a natural product that can be found in spinach and rhubarb leaves .
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Cat. No.: HY-L243
95 compounds

Quinone compounds are a significant class of natural products featuring a conjugated quinone structure, widely distributed in plants, fungi, and microorganisms. Based on their core structures, they can be primarily categorized into benzoquinones, naphthoquinones, phenanthrenequinones, and anthraquinones, among others. This structural diversity endows quinone compounds with a broad spectrum of pharmacological activities, making them key components in traditional Chinese medicine (such as rhubarb, Lithospermum erythrorhizon, and Salvia miltiorrhiza). Modern research has confirmed that their activities encompass anti-tumor, anti-inflammatory, antibacterial, antiviral, antiplatelet aggregation, and neuroprotective effects, among others, establishing them as an important source for drug development.

MCE designs a unique collection of 95 quinones that all come from natural products. MCE Quinones Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

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