3 Results for "

sPLA2-IIA Inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "sPLA2-IIA Inhibitor" in MCE Product Catalog:

Cat. No.: HY-P10053
CAS No.: 236394-37-9
Target:  

Phospholipase

Research Areas:  

Metabolic Disease

sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .
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Cat. No.: HY-N7327
CAS No.: 50276-96-5
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases .
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Cat. No.: HY-112605
CAS No.: 2241025-50-1
Target:  

Phospholipase

Research Areas:  

Cardiovascular Disease

sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively .
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