6 Results for "

sphingosine biosynthesis

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "sphingosine biosynthesis" in MCE Product Catalog:

  • Targets Recommended:
9
Fumonisin B1
Fumonisin B1
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9 Cited Publications
Cat. No.: HY-N6719
CAS No.: 116355-83-0
Category:  

Infection Human Gut Microbiota Metabolites Microorganisms Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics

Target:  

Acyltransferase

Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
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2
Palmitoyl coenzyme A lithium
Palmitoyl coenzyme A lithium
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2 Cited Publications
Cat. No.: HY-134427
CAS No.: 188174-64-3
Purity:  96.00%
Synonyms: Palmitoyl CoA lithium
Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis .
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Fumonisin B2
Fumonisin B2
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Cat. No.: HY-N6723
CAS No.: 116355-84-1
Category:  

Infection Human Gut Microbiota Metabolites Microorganisms Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics

Target:  

Ceramidase Acyltransferase

Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin with toxicity comparable to that of Fumonisin B1 (HY-N6719). Fumonisin B2 inhibits de novo sphingolipid biosynthesis by blocking the amide bond formation between fatty acids and dihydrosphingosine, which leads to a massive intracellular accumulation of free dihydrosphingosine, altered sphingosine levels, subsequent inhibition of cell proliferation, and induction of cell death. Fumonisin B2 is used to investigate the pathogenesis of diseases associated with Fusarium verticillioides contamination, including equine leukoencephalomalacia, porcine pulmonary edema syndrome, human esophageal cancer, and rat hepatocellular carcinoma .
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Fumonisin B2-13C34
Fumonisin B2-13C34
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Cat. No.: HY-N6723S
CAS No.: 1217481-36-1
Fumonisin B2- 13C34 is the 13C labeled Fumonisin B2 (HY-N6723) . Fumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis .
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Fumonisin B1-13C34
Fumonisin B1-13C34
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Cat. No.: HY-N6719S
CAS No.: 1217458-62-2
Fumonisin B1- 13C34 is the 13C labeled Fumonisin B1 (HY-N6719) . Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin .
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Ganglioside GD3 (d18:1/12:0)
Ganglioside GD3 (d18:1/12:0)
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Cat. No.: HY-148747
CAS No.: 138749-26-5
Target:  

Biochemical Assay Reagents

Research Areas:  

Neurological Disease Cancer

Ganglioside GD3 (d18:1/12:0) is a type of glycosphingolipid, the d18:1 indicates the sphingosine base, and the 12:0 represents the fatty acid part which is lauric acid. Ganglioside GD3 (d18:1/12:0) is a crucial intermediate in the biosynthesis pathway of gangliosides and is mainly found in the brain tissues of mammals. Ganglioside GD3 (d18:1/12:0) plays significant roles in development, cell signal transduction, and various diseases .
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