Palmitoyl coenzyme A lithium
Based on 2 publication(s) in Google Scholar
Palmitoyl coenzyme A lithium is an acyl-CoA thioester that can be transported into the mitochondrial matrix via the carnitine shuttle system and is involved in β-oxidation. Palmitoyl coenzyme A lithium can also be used as a substrate for sphingosine biosynthesis.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 188174-64-3
- Formula: C37H66N7O17P3S.xLi
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Palmitoyl coenzyme A lithium
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Palmitoyl coenzyme A lithium (100 μM) reversibly inhibits acetyl coenzyme A carboxylase activity from chicken hepatocytes and is competitive with citric acid and has an important role in the regulation of fatty acid synthesis in vivo[1].
Palmitoyl coenzyme A lithium with a high levels in mitochondria reduces the entry of ADP, which leads to an increased inhibition of glutamate dehydrogenase by palmitoyl CoA[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 188174-64-3
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Appearance Solid
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Formula C37H66N7O17P3S.xLi
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Color White to off-white
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SMILES
O[C@H]1[C@@H](O[C@@H]([C@H]1OP(O)(O)=O)COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCCCCCCCCCC)=O)=O)=O)(O)=O)(O)=O)N2C3=NC=NC(N)=C3N=C2.[x].[Li]
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Synonyms
Palmitoyl CoA lithium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Nat Commun
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm. [Abstract]2025 Aug 23;16(1):7864. PMID: 40849303 -
Aging Cell
Aging Triggers an Intestinal Energy Crisis and HDL3 Deficiency Disrupting Gut-Liver Axis Homeostasis. [Abstract]2026 Mar;25(3):e70445. PMID: 41851037
Solvent & Solubility
H2O : ≥ 33.33 mg/mL
* "≥" means soluble, but saturation unknown.
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. A G Goodridge, et al. Regulation of the activity of acetyl coenzyme A carboxylase by palmitoyl coenzyme A and citrate. J Biol Chem. 1972 Nov 10;247(21):6946-52. [Content Brief]
[2]. L A Fahien, et al. Regulation of glutamate dehydrogenase by palmitoyl-coenzyme A. Arch Biochem Biophys. 1981 Nov;212(1):247-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)