1217458-62-2
Chemical Structure
Fumonisin B1-13C34
- CAS No.: 1217458-62-2
- Formula:13C34H59NO15
- Molecular Weight:755.58
IUPAC Name: (2R,2'R)-2,2'-((((5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-11,16,18-trihydroxy-5,9-di(methyl-13C)icosane-6,7-diyl-1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20-13C20)bis(oxy))bis(2-oxoethane-2,1-diyl-1,2-13C2))disuccinic-13C4 acid
InChIKey: UVBUBMSSQKOIBE-HTPIOKJKSA-N
SMILES: O[13C]([13CH2][13C@@H]([13C](O)=O)[13CH2][13C](O[13C@@H]([13CH2][13C@@H]([13CH3])[13CH2][13C@H](O)[13CH2][13CH2][13CH2][13CH2][13C@@H](O)[13CH2][13C@H](O)[13C@@H](N)[13CH3])[13C@@H]([13C@H]([13CH3])[13CH2][13CH2][13CH2][13CH3])O[13C]([13CH2][13C@H]([13C](O)=O)[13CH2][13C](O)=O)=O)=O)=O
Biological Activity:
Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719)[1]. Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin[2][3].
The product specifications provided below refer solely to the active content of Fumonisin B1-13C34.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fumonisin B1-13C34 | 98.5% | Fumonisin B1-13C34 is the 13C labeled Fumonisin B1 (HY-N6719). Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin. The product specifications provided below refer solely to the active content of Fumonisin B1-13C34. |
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Fumonisin B1 | 99.90% | Fumonisin B1 is a mycotoxin produced from Fusarium moniliforme. Fumonisin B1 is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis. Fumonisin B1 is the most abundant and toxic fumonisin. | ||||||||||||||||||||
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Similarity Score 0.92
HY-N6723Fumonisin B2 -
Similarity Score 0.92
HY-N6723SFumonisin B2-13C34 -
Similarity Score 0.92
HY-N6726Fumonisin B3 -
Similarity Score 0.92
HY-N6726SFumonisin B3-13C34 -
Similarity Score 0.92
HY-N6726S1Fumonisin B3-13C34-1 -
Similarity Score 0.86
HY-N12329Fumonisin B4 -
Similarity Score 0.60
HY-N6730Hydrolyzed Fumonisin B1 -
Similarity Score 0.60
HY-N14061Halymecin D -
Similarity Score 0.60
HY-N14062Halymecin E -
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220. [Content Brief]
- [2]. Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7. [Content Brief]
- [3]. Wang SK, et al. Effect of fumonisin B₁ on the cell cycle of normal human liver cells. Mol Med Rep. 2013 Jun;7(6):1970-6. [Content Brief]
