127 Results for "

steroidal compound

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "steroidal compound" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-120012
CAS No.: 1893415-00-3
Purity:  99.71%
Synonyms: AZD9567
Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation .
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7
7 Publications Verification
Cat. No.: HY-18102
CAS No.: 1215085-92-9
Target:  

Androgen Receptor

Research Areas:  

Neurological Disease

GLPG0492 is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy .
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4
4 Cited Publications
Cat. No.: HY-133017
CAS No.: 2114339-57-8
Purity:  99.79%
Synonyms: SAR439859
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

SAR439859 (compound 43d) is an orally active, non-steroidal, and selective estrogen receptor degrader (SERD). SAR439859 is an effective ER antagonist with ER degradation activity, an EC50 of 0.2 nM. SAR439859 can show potent anti-tumor effects and limited cross-resistance in ER + breast cancer.
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Cat. No.: HY-76251
CAS No.: 41340-25-4
Synonyms: AY-24236
Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that can cross the blood-brain barrier and is a non-selective inhibitor of COX (IC50=53.5 nM)
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Cat. No.: HY-107819
CAS No.: 80-97-7
Purity:  99.92%
Synonyms: Dihydrocholesterol; 5α-Cholestanol; NSC 18188
5α-Cholestan-3β-ol is a derivitized steroid compound.
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Cat. No.: HY-N0386
CAS No.: 61371-55-9
Griffonilide is a steroidal compound that can be isolated from the roots of Semiaquilegia adoxoides .
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Cat. No.: HY-B0743A
CAS No.: 52212-02-9
Target:  

nAChR

Research Areas:  

Neurological Disease

Pipecuronium bromide is a potent long-acting nondepolarizing steroidal neuromuscular blocking agent (NMBA), and a bisquaternary ammonium compound. Pipecuronium bromide is a powerful competitive nAChR antagonist with a Kd of 3.06 μM .
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Cat. No.: HY-N3505
CAS No.: 1111088-89-1
14-Hydroxy sprengerinin C is a steroidal compound found in Ophiopogon japonicus.
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Cat. No.: HY-W009347
CAS No.: 20170-32-5
Target:  

COX

Research Areas:  

Inflammation/Immunology

COX-1-IN-3 (compound 19) is a COX-1 inhibitor with non-steroidal anti-inflammatory activity .
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Cat. No.: HY-128683
CAS No.: 23185-94-6
Purity:  ≥98.0%
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound that may induce cyclopia in pregnant Mianyang embryos .
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Cat. No.: HY-N1375
CAS No.: 84745-94-8
Qingyanshengenin (NSC 379666; compound 2), a pregnane glycoside, is a C21 steroidal aglycone isolated from the root of Cynanchumot ophyllum (Asclepiadaceae). Qingyanshengenin has anti-cancer activity .
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Cat. No.: HY-N0181A
CAS No.: 474-69-1
Synonyms: 9β,10α-Ergosterol
Lumisterol (9β,10α-Ergosterol), a steroid compound, is the (9β,10α)-stereoisomer of Ergosterol (HY-N0181). Lumisterol is a photoprotective agent against UVB-induced DNA damage and anti-proliferative activities .
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Cat. No.: HY-156530
CAS No.: 2744168-51-0
Purity:  99.64%
Target:  

Cytochrome P450

Research Areas:  

Endocrinology

CYP11A1-IN-1 (compound 30) is an inhibitor of CYP11A1, with IC50 value of 201-2000 nM. CYP11A1-IN-1 can be used for research in steroid receptor, particularly androgen receptor, dependent diseases and conditions, such as prostate cancer .
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Cat. No.: HY-W102516
CAS No.: 1162-56-7
Synonyms: Δ6-Progesterone
6-Dehydroprogesterone (Δ6-Progesterone) is a steroid compound that can be found in Botryodiplodia theobromae. 6-Dehydroprogesterone is a metabolic product of Progesterone (HY-N0437) after a microbial dehydrogenation reaction. 6-Dehydroprogesterone can be used to study steroid metabolism pathways, microbial dehydrogenase activity, and the biotransformation of steroids .
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Cat. No.: HY-B1079
CAS No.: 27470-51-5
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

Suxibuzone is a compound used for the study of joint and muscle pain, and it is a prodrug of the non-steroidal anti-inflammatory drug Phenylbutazone.
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Cat. No.: HY-107961
CAS No.: 33564-31-7
Purity:  99.86%
Research Areas:  

Inflammation/Immunology

Diflorasone diacetate is an anti-inflammatory steroid compound used as locally or topically agent. Diflorasone diacetate is being used for skin disorders to control corticosteroid-responsive dermatoses .
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Cat. No.: HY-B2175
CAS No.: 23413-80-1
Synonyms: Aluminum diacetylsalicylate
Research Areas:  

Inflammation/Immunology

Aspirin Aluminum is a novel intermolecular compound which can inhibit gastrointestinal mucosal disorders induced by NSAIDs (non-steroidal anti-inflammatory agents) extracted from patent WO 2010064441 A1.
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Cat. No.: HY-107819S
CAS No.: 2260669-14-3
Purity:  99.18%
Synonyms: Dihydrocholesterol-d5; 5α-Cholestanol-d5; NSC 18188-d5
5α-Cholestan-3β-ol-d5 is the deuterium labeled 5α-Cholestan-3β-ol. 5α-Cholestan-3β-ol is a derivitized steroid compound .
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Cat. No.: HY-106566
CAS No.: 66734-13-2
Synonyms: Sch 22219
Research Areas:  

Inflammation/Immunology

Alclometasone dipropionate (Sch 22219) is a steroid compound. Alclometasone dipropionate can be used for the research of dermatitis and skin itch .
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Cat. No.: HY-163162
CAS No.: 3029806-33-2
Anhydro-Ouabain (compound 20) is a cardiotonic steroid which shows anti-inflammatory and neuroprotective activities and thus can be used in neurological research .
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