1893415-00-3
Chemical Structure
Mizacorat
Synonym(s): AZD9567
- CAS No.: 1893415-00-3
- Formula:C27H28F2N4O3
- Molecular Weight:494.53
IUPAC Name: 2,2-difluoro-N-((1R,2S)-3-methyl-1-((1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yl)oxy)-1-phenylbutan-2-yl)propanamide
InChIKey: ZQFNDBISEYQVRR-LOSJGSFVSA-N
SMILES: CC(F)(F)C(N[C@H]([C@H](OC1=CC2=C(N(C(C=C3)=CN(C)C3=O)N=C2)C=C1)C4=CC=CC=C4)C(C)C)=O
Biological Activity: Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].
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Mizacorat | 99.27% | Mizacorat (AZD9567; compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. Exhibits excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation. | ||||||||||||||||||||
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Keywords
